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10.1016/S1473-3099(20)30589-2 http://scihub22266oqcxt.onion/10.1016/S1473-3099(20)30589-2 32758438!7398038!32758438     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Lancet+Infect+Dis 2020 ; 20 (12): 1401-1408 Nephropedia Template TP {{tp|p=32758438|t=2020. Risk of COVID-19 in health-care workers in Denmark: an observational cohort study |pdf=|usr=}}{{32758438}} gab.com Text Risk of COVID-19 in health-care workers in Denmark: an observational cohort study JO: Lancet Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32758438 #FOAvip BACKGROUND: Health-care workers are thought to be highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We aimed to investigate the prevalence of antibodies against SARS-CoV-2 in health-care workers and the proportion of seroconverted health-care workers with previous symptoms of COVID-19. METHODS: In this observational cohort study, screening was offered to health-care workers in the Capital Region of Denmark, including medical, nursing, and other students who were associated with hospitals in the region. Screening included point-of-care tests for IgM and IgG antibodies against SARS-CoV-2. Test results and participant characteristics were recorded. Results were compared with findings in blood donors in the Capital Region in the study period. FINDINGS: Between April 15 and April 23, 2020, we screened 29 295 health-care workers, of whom 28 792 (98.28%) provided their test results. We identified 1163 (4.04% [95% CI 3.82-4.27]) seropositive health-care workers. Seroprevalence was higher in health-care workers than in blood donors (142 [3.04%] of 4672; risk ratio [RR] 1.33 [95% CI 1.12-1.58]; p<0.001). Seroprevalence was higher in male health-care workers (331 [5.45%] of 6077) than in female health-care workers (832 [3.66%] of 22 715; RR 1.49 [1.31-1.68]; p<0.001). Frontline health-care workers working in hospitals had a significantly higher seroprevalence (779 [4.55%] of 16 356) than health-care workers in other settings (384 [3.29%] of 11 657; RR 1.38 [1.22-1.56]; p<0.001). Health-care workers working on dedicated COVID-19 wards (95 [7.19%] of 1321) had a significantly higher seroprevalence than other frontline health-care workers working in hospitals (696 [4.35%] of 15 983; RR 1.65 [1.34-2.03]; p<0.001). 622 [53.5%] of 1163 seropositive participants reported symptoms attributable to SARS-CoV-2. Loss of taste or smell was the symptom that was most strongly associated with seropositivity (377 [32.39%] of 1164 participants with this symptom were seropositive vs 786 [2.84%] of 27 628 without this symptom; RR 11.38 [10.22-12.68]). The study is registered at ClinicalTrials.gov, NCT04346186. INTERPRETATION: The prevalence of health-care workers with antibodies against SARS-CoV-2 was low but higher than in blood donors. The risk of SARS-CoV-2 infection in health-care workers was related to exposure to infected patients. More than half of seropositive health-care workers reported symptoms attributable to COVID-19. FUNDING: Lundbeck Foundation. Twit Text FOAVip Risk of COVID-19 in health-care workers in Denmark: an observational cohort study ????Lancet Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32758438 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32758438 #FOAvip English Wikipedia <ref>{{Cite pmid|32758438}}</ref> Risk of COVID-19 in health-care workers in Denmark: an observational cohort study #MMPMID32758438 Iversen K; Bundgaard H; Hasselbalch RB; Kristensen JH; Nielsen PB; Pries-Heje M; Knudsen AD; Christensen CE; Fogh K; Norsk JB; Andersen O; Fischer TK; Jensen CAJ; Larsen M; Torp-Pedersen C; Rungby J; Ditlev SB; Hageman I; Mogelvang R; Hother CE; Gybel-Brask M; Sorensen E; Harritshoj L; Folke F; Sten C; Benfield T; Nielsen SD; Ullum H Lancet Infect Dis 2020[Dec]; 20 (12): 1401-1408 PMID32758438show ga BACKGROUND: Health-care workers are thought to be highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We aimed to investigate the prevalence of antibodies against SARS-CoV-2 in health-care workers and the proportion of seroconverted health-care workers with previous symptoms of COVID-19. METHODS: In this observational cohort study, screening was offered to health-care workers in the Capital Region of Denmark, including medical, nursing, and other students who were associated with hospitals in the region. Screening included point-of-care tests for IgM and IgG antibodies against SARS-CoV-2. Test results and participant characteristics were recorded. Results were compared with findings in blood donors in the Capital Region in the study period. FINDINGS: Between April 15 and April 23, 2020, we screened 29 295 health-care workers, of whom 28 792 (98.28%) provided their test results. We identified 1163 (4.04% [95% CI 3.82-4.27]) seropositive health-care workers. Seroprevalence was higher in health-care workers than in blood donors (142 [3.04%] of 4672; risk ratio [RR] 1.33 [95% CI 1.12-1.58]; p<0.001). Seroprevalence was higher in male health-care workers (331 [5.45%] of 6077) than in female health-care workers (832 [3.66%] of 22 715; RR 1.49 [1.31-1.68]; p<0.001). Frontline health-care workers working in hospitals had a significantly higher seroprevalence (779 [4.55%] of 16 356) than health-care workers in other settings (384 [3.29%] of 11 657; RR 1.38 [1.22-1.56]; p<0.001). Health-care workers working on dedicated COVID-19 wards (95 [7.19%] of 1321) had a significantly higher seroprevalence than other frontline health-care workers working in hospitals (696 [4.35%] of 15 983; RR 1.65 [1.34-2.03]; p<0.001). 622 [53.5%] of 1163 seropositive participants reported symptoms attributable to SARS-CoV-2. Loss of taste or smell was the symptom that was most strongly associated with seropositivity (377 [32.39%] of 1164 participants with this symptom were seropositive vs 786 [2.84%] of 27 628 without this symptom; RR 11.38 [10.22-12.68]). The study is registered at ClinicalTrials.gov, NCT04346186. INTERPRETATION: The prevalence of health-care workers with antibodies against SARS-CoV-2 was low but higher than in blood donors. The risk of SARS-CoV-2 infection in health-care workers was related to exposure to infected patients. More than half of seropositive health-care workers reported symptoms attributable to COVID-19. FUNDING: Lundbeck Foundation. |Adult[MESH] |Antibodies, Viral/blood[MESH] |Blood Donors/statistics & numerical data[MESH] |COVID-19/diagnosis/*epidemiology/immunology/pathology[MESH] |Cohort Studies[MESH] |Denmark/epidemiology[MESH] |Female[MESH] |Health Personnel/classification/*statistics & numerical data[MESH] |Humans[MESH] |Immunoglobulin G/blood[MESH] |Immunoglobulin M/blood[MESH] |Male[MESH] |Middle Aged[MESH] |Occupational Health/*statistics & numerical data[MESH] |Point-of-Care Testing[MESH] |SARS-CoV-2/immunology/isolation & purification[MESH] |Seroconversion[MESH]Risk of COVID-19 in health-care workers in Denmark: an observational c(epmc).pdf DeepDyve Pubget Overpricing