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10.1186/s13148-020-00912-7 http://scihub22266oqcxt.onion/10.1186/s13148-020-00912-7 32758273!7404079!32758273     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Epigenetics 2020 ; 12 (1): 118 Nephropedia Template TP {{tp|p=32758273|t=2020. Management of epigenomic networks entailed in coronavirus infections and COVID-19 |pdf=|usr=}}{{32758273}} gab.com Text Management of epigenomic networks entailed in coronavirus infections and COVID-19 JO: Clin Epigenetics http://www.kidney.de/pget.php?&tw=1&pmid=32758273 #FOAvip Coronaviruses (CoVs) are highly diverse single-stranded RNA viruses owing to their susceptibility to numerous genomic mutations and recombination. Such viruses involve human and animal pathogens including the etiologic agents of acute respiratory tract illnesses: severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the highly morbific SARS-CoV-2. Coronavirus disease 2019 (COVID-19), an emerging disease with a quick rise in infected cases and deaths, was recently identified causing a worldwide pandemic. COVID-19 disease outcomes were found to increase in elderly and patients with a compromised immune system. Evidences indicated that the main culprit behind COVID-19 deaths is the cytokine storm, which is illustrated by an uncontrolled over-production of soluble markers of inflammation. The regulation process of coronavirus pathogenesis through molecular mechanism comprise virus-host interactions linked to viral entry, replication and transcription, escape, and immune system control. Recognizing coronavirus infections and COVID-19 through epigenetics lens will lead to potential alteration in gene expression thus limiting coronavirus infections. Focusing on epigenetic therapies reaching clinical trials, clinically approved epigenetic-targeted agents, and combination therapy of antivirals and epigenetic drugs is currently considered an effective and valuable approach for viral replication and inflammatory overdrive control. Twit Text FOAVip Management of epigenomic networks entailed in coronavirus infections and COVID-19 ????Clin Epigenetics http://www.kidney.de/pget.php?&tw=1&pmid=32758273 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32758273 #FOAvip English Wikipedia <ref>{{Cite pmid|32758273}}</ref> Management of epigenomic networks entailed in coronavirus infections and COVID-19 #MMPMID32758273 El Baba R; Herbein G Clin Epigenetics 2020[Aug]; 12 (1): 118 PMID32758273show ga Coronaviruses (CoVs) are highly diverse single-stranded RNA viruses owing to their susceptibility to numerous genomic mutations and recombination. Such viruses involve human and animal pathogens including the etiologic agents of acute respiratory tract illnesses: severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the highly morbific SARS-CoV-2. Coronavirus disease 2019 (COVID-19), an emerging disease with a quick rise in infected cases and deaths, was recently identified causing a worldwide pandemic. COVID-19 disease outcomes were found to increase in elderly and patients with a compromised immune system. Evidences indicated that the main culprit behind COVID-19 deaths is the cytokine storm, which is illustrated by an uncontrolled over-production of soluble markers of inflammation. The regulation process of coronavirus pathogenesis through molecular mechanism comprise virus-host interactions linked to viral entry, replication and transcription, escape, and immune system control. Recognizing coronavirus infections and COVID-19 through epigenetics lens will lead to potential alteration in gene expression thus limiting coronavirus infections. Focusing on epigenetic therapies reaching clinical trials, clinically approved epigenetic-targeted agents, and combination therapy of antivirals and epigenetic drugs is currently considered an effective and valuable approach for viral replication and inflammatory overdrive control. |*Betacoronavirus/genetics/physiology[MESH] |*Coronavirus Infections/epidemiology/virology[MESH] |*Pandemics[MESH] |*Pneumonia, Viral/epidemiology/virology[MESH] |COVID-19[MESH] |Drug Discovery/methods[MESH] |Epigenomics/*methods[MESH] |Genome, Viral/drug effects[MESH] |Humans[MESH]Management of epigenomic networks entailed in coronavirus infections a(epmc).pdf DeepDyve Pubget Overpricing