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10.1097/MD.0000000000021597

http://scihub22266oqcxt.onion/10.1097/MD.0000000000021597
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32756215!7402741!32756215
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suck abstract from ncbi


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pmid32756215      Medicine+(Baltimore) 2020 ; 99 (31): e21597
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  • Therapeutic response to corticosteroids in a critically ill patient with COVID-19: A case report #MMPMID32756215
  • Wang K; Tan F; Zhou R; Liu D; Ni Z; Liu J; Luo F
  • Medicine (Baltimore) 2020[Jul]; 99 (31): e21597 PMID32756215show ga
  • INTRODUCTION: Since the coronavirus disease 2019 (COVID-19) outbreak in Wuhan in late 2019, controversy on the use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids. PATIENT CONCERNS: A 53-year-old critically ill woman from Wuhan suffered with COVID-19. DIAGNOSIS: The chest computed tomography scan was suggestive of COVID-19. The diagnosis was confirmed by a real-time reverse transcription polymerase chain reaction test for SARS-CoV-2. The critically ill status was characterized by worsening dyspnea, progressing bilateral lung consolidation, and poor oxygenation (SiO2/FiO2:110 mm Hg). INTERVENTIONS: The patient was treated with a moderate dose of intravenous corticosteroids and high-flow nasal cannula oxygen therapy. OUTCOMES: After the initiation of corticosteroids, the patient rapidly improved over the following 6 days. Serial chest computed tomography scans showed good absorption of the consolidations. The patient was discharged on Day 17 of hospitalization without obvious adverse effects. CONCLUSIONS: Early use of moderate-dose corticosteroids over a short period may enhance recovery from COVID-19 in critically ill patients.
  • |Adrenal Cortex Hormones/*administration & dosage[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Combined Modality Therapy[MESH]
  • |Coronavirus Infections/*drug therapy/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]
  • |Oxygen Inhalation Therapy/*methods[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy/virology[MESH]
  • |SARS-CoV-2[MESH]


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