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10.1159/000509007

http://scihub22266oqcxt.onion/10.1159/000509007
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32756065!7949238!32756065
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suck abstract from ncbi


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pmid32756065      Respiration 2020 ; 99 (8): 667-677
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  • Inpatient Care during the COVID-19 Pandemic: A Survey of Italian Physicians #MMPMID32756065
  • Attanasi M; Pasini S; Caronni A; Pellegrino GM; Faverio P; Di Pillo S; Cimino MM; Cipolla G; Chiarelli F; Centanni S; Sferrazza Papa GF
  • Respiration 2020[]; 99 (8): 667-677 PMID32756065show ga
  • BACKGROUND: Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern. OBJECTIVE: We explored the clinical management of inpatients with COVID-19 in Italy. METHODS: A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. A panel of experts was selected according to their clinical curricula and their responses were analyzed. RESULTS: A total of 1,215 physicians completed the survey questionnaire (17.4% response rate). Of these, 188 (15.5%) were COVID-19 experts. Chest computed tomography was the most used method to detect and monitor COVID-19 pneumonia. Most of the experts managed acute respiratory failure with CPAP (56.4%), high flow nasal cannula (18.6%), and non-invasive mechanical ventilation (8%), while an intensivist referral for early intubation was requested in 17% of the cases. Hydroxychloroquine was prescribed as an antiviral in 90% of cases, both as monotherapy (11.7%), and combined with protease inhibitors (43.6%) or azithromycin (36.2%). The experts unanimously prescribed low-molecular-weight heparin to patients with severe COVID-19 pneumonia, and half of them (51.6%) used a dose higher than standard. The respiratory burden in patients who survived the acute phase was estimated as relevant in 28.2% of the cases, modest in 39.4%, and negligible in 9%. CONCLUSIONS: In our survey some major topics, such as the role of non-invasive respiratory support and drug treatments, show disagreement between experts, likely reflecting the absence of high-quality evidence studies. Considering the significant respiratory sequelae reported following COVID-19, proper respiratory and physical therapy programs should be promptly made available.
  • |*Hospitalization[MESH]
  • |*Practice Patterns, Physicians'[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Anti-Bacterial Agents/*therapeutic use[MESH]
  • |Anticoagulants/therapeutic use[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Azithromycin/therapeutic use[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Cannula[MESH]
  • |Cardiology[MESH]
  • |Continuous Positive Airway Pressure/methods[MESH]
  • |Coronavirus Infections/complications/diagnosis/drug therapy/*therapy[MESH]
  • |Critical Care[MESH]
  • |Heparin, Low-Molecular-Weight/therapeutic use[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/therapeutic use[MESH]
  • |Intensive Care Units[MESH]
  • |Internal Medicine[MESH]
  • |Italy[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Middle Aged[MESH]
  • |Noninvasive Ventilation/methods[MESH]
  • |Pandemics[MESH]
  • |Physicians[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*therapy[MESH]
  • |Protease Inhibitors/*therapeutic use[MESH]
  • |Pulmonary Medicine[MESH]
  • |Referral and Consultation[MESH]
  • |Respiration, Artificial/*methods[MESH]
  • |Respiratory Insufficiency/etiology/*therapy[MESH]
  • |SARS-CoV-2[MESH]
  • |Surveys and Questionnaires[MESH]


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