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10.4269/ajtmh.20-0688

http://scihub22266oqcxt.onion/10.4269/ajtmh.20-0688
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32755528!7470588!32755528
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suck abstract from ncbi


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pmid32755528      Am+J+Trop+Med+Hyg 2020 ; 103 (3): 1207-1210
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  • Household Clustering of SARS-CoV-2 in Community Settings: A Study from Rural Ecuador #MMPMID32755528
  • Del Brutto OH; Costa AF; Mera RM; Recalde BY; Bustos JA; Garcia HH
  • Am J Trop Med Hyg 2020[Sep]; 103 (3): 1207-1210 PMID32755528show ga
  • The SARS-CoV-2 pandemic is now expanding into the developing world with devastating consequences. Departing from a population-based study in rural Ecuador where all adult individuals (aged 40 years or older) were tested for SARS-CoV-2 IgG and IgM antibodies, we expanded it to include a house-based case-control component assessing in-house clustering and other variables potentially associated with infection. We selected houses where exactly two study participants lived and were both seropositive (case-houses), and matched 1:1 to control-houses where both were seronegative. Younger household members had an antibody test performed. Infected household members were found in 33 (92%) case-houses and in only six (17%) control-houses. In 28/29 discordant house pairs, the case-house had seropositive household members and the control-house did not (odds ratio: 28; 95% CI: 4.6-1,144). Our data demonstrate strong in-house clustering of infection in community settings, stressing the importance of early case ascertainment and isolation for SARS-CoV-2 control.
  • |*Betacoronavirus[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |COVID-19[MESH]
  • |Case-Control Studies[MESH]
  • |Child[MESH]
  • |Cluster Analysis[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Ecuador/epidemiology[MESH]
  • |Family Characteristics[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |Immunoglobulin M/blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology[MESH]
  • |SARS-CoV-2[MESH]


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