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10.1161/STROKEAHA.120.030397

http://scihub22266oqcxt.onion/10.1161/STROKEAHA.120.030397
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32755349!7434004!32755349
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suck abstract from ncbi


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pmid32755349      Stroke 2020 ; 51 (9): 2656-2663
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  • Emergent Large Vessel Occlusion Stroke During New York City s COVID-19 Outbreak: Clinical Characteristics and Paraclinical Findings #MMPMID32755349
  • Majidi S; Fifi JT; Ladner TR; Lara-Reyna J; Yaeger KA; Yim B; Dangayach N; Oxley TJ; Shigematsu T; Kummer BR; Stein LK; Weinberger J; Fara MG; De Leacy R; Dhamoon MS; Tuhrim S; Mocco J
  • Stroke 2020[Sep]; 51 (9): 2656-2663 PMID32755349show ga
  • BACKGROUND AND PURPOSE: The 2019 novel coronavirus outbreak and its associated disease (coronavirus disease 2019 [COVID-19]) have created a worldwide pandemic. Early data suggest higher rate of ischemic stroke in severe COVID-19 infection. We evaluated whether a relationship exists between emergent large vessel occlusion (ELVO) and the ongoing COVID-19 outbreak. METHODS: This is a retrospective, observational case series. Data were collected from all patients who presented with ELVO to the Mount Sinai Health System Hospitals across New York City during the peak 3 weeks of hospitalization and death from COVID-19. Patients' demographic, comorbid conditions, cardiovascular risk factors, COVID-19 disease status, and clinical presentation were extracted from the electronic medical record. Comparison was made between COVID-19 positive and negative cohorts. The incidence of ELVO stroke was compared with the pre-COVID period. RESULTS: Forty-five consecutive ELVO patients presented during the observation period. Fifty-three percent of patients tested positive for COVID-19. Total patients' mean (+/-SD) age was 66 (+/-17). Patients with COVID-19 were significantly younger than patients without COVID-19, 59+/-13 versus 74+/-17 (odds ratio [95% CI], 0.94 [0.81-0.98]; P=0.004). Seventy-five percent of patients with COVID-19 were male compared with 43% of patients without COVID-19 (odds ratio [95% CI], 3.99 [1.12-14.17]; P=0.032). Patients with COVID-19 were less likely to be White (8% versus 38% [odds ratio (95% CI), 0.15 (0.04-0.81); P=0.027]). In comparison to a similar time duration before the COVID-19 outbreak, a 2-fold increase in the total number of ELVO was observed (estimate: 0.78 [95% CI, 0.47-1.08], P
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Arterial Occlusive Diseases/complications/*epidemiology[MESH]
  • |Black People/statistics & numerical data[MESH]
  • |Brain Ischemia/complications/*epidemiology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/complications/*epidemiology[MESH]
  • |Electronic Health Records[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |New York City[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/*epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |Sex Factors[MESH]
  • |Stroke/complications/*epidemiology[MESH]


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