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10.1152/ajplung.00252.2020 http://scihub22266oqcxt.onion/10.1152/ajplung.00252.2020 32755307!7473886!32755307     free     free     free Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Physiol+Lung+Cell+Mol+Physiol 2020 ; 319 (3): L444-L455 Nephropedia Template TP {{tp|p=32755307|t=2020. SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs |pdf=|usr=}}{{32755307}} gab.com Text SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs JO: Am J Physiol Lung Cell Mol Physiol http://www.kidney.de/pget.php?&tw=1&pmid=32755307 #FOAvip Cold viruses have generally been considered fairly innocuous until the appearance of the severe acute respiratory coronavirus 2 (SARS-CoV-2) in 2019, which caused the coronavirus disease 2019 (COVID-19) global pandemic. Two previous viruses foreshadowed that a coronavirus could potentially have devastating consequences in 2002 [severe acute respiratory coronavirus (SARS-CoV)] and in 2012 [Middle East respiratory syndrome coronavirus (MERS-CoV)]. The question that arises is why these viruses are so different from the relatively harmless cold viruses. On the basis of an analysis of the current literature and using bioinformatic approaches, we examined the potential human miRNA interactions with the SARS-CoV-2's genome and compared the miRNA target sites in seven coronavirus genomes that include SARS-CoV-2, MERS-CoV, SARS-CoV, and four nonpathogenic coronaviruses. Here, we discuss the possibility that pathogenic human coronaviruses, including SARS-CoV-2, could modulate host miRNA levels by acting as miRNA sponges to facilitate viral replication and/or to avoid immune responses. Twit Text FOAVip SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs ????Am J Physiol Lung Cell Mol Physiol http://www.kidney.de/pget.php?&tw=1&pmid=32755307 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32755307 #FOAvip English Wikipedia <ref>{{Cite pmid|32755307}}</ref> SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs #MMPMID32755307 Bartoszewski R; Dabrowski M; Jakiela B; Matalon S; Harrod KS; Sanak M; Collawn JF Am J Physiol Lung Cell Mol Physiol 2020[Sep]; 319 (3): L444-L455 PMID32755307show ga Cold viruses have generally been considered fairly innocuous until the appearance of the severe acute respiratory coronavirus 2 (SARS-CoV-2) in 2019, which caused the coronavirus disease 2019 (COVID-19) global pandemic. Two previous viruses foreshadowed that a coronavirus could potentially have devastating consequences in 2002 [severe acute respiratory coronavirus (SARS-CoV)] and in 2012 [Middle East respiratory syndrome coronavirus (MERS-CoV)]. The question that arises is why these viruses are so different from the relatively harmless cold viruses. On the basis of an analysis of the current literature and using bioinformatic approaches, we examined the potential human miRNA interactions with the SARS-CoV-2's genome and compared the miRNA target sites in seven coronavirus genomes that include SARS-CoV-2, MERS-CoV, SARS-CoV, and four nonpathogenic coronaviruses. Here, we discuss the possibility that pathogenic human coronaviruses, including SARS-CoV-2, could modulate host miRNA levels by acting as miRNA sponges to facilitate viral replication and/or to avoid immune responses. |*Virus Replication[MESH] |Betacoronavirus/*immunology/*isolation & purification[MESH] |COVID-19[MESH] |Coronavirus Infections/immunology/*virology[MESH] |Humans[MESH] |MicroRNAs/*genetics/*immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/immunology/*virology[MESH]SARS-CoV-2 may regulate cellular responses through depletion of specif(epmc).pdf DeepDyve Pubget Overpricing