Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/ijms21155475 http://scihub22266oqcxt.onion/10.3390/ijms21155475 32751841!7432482!32751841     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2020 ; 21 (15): ä Nephropedia Template TP {{tp|p=32751841|t=2020. SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms |pdf=|usr=}}{{32751841}} gab.com Text SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32751841 #FOAvip Increasing evidence suggests that Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2) can also invade the central nervous system (CNS). However, findings available on its neurological manifestations and their pathogenic mechanisms have not yet been systematically addressed. A literature search on neurological complications reported in patients with COVID-19 until June 2020 produced a total of 23 studies. Overall, these papers report that patients may exhibit a wide range of neurological manifestations, including encephalopathy, encephalitis, seizures, cerebrovascular events, acute polyneuropathy, headache, hypogeusia, and hyposmia, as well as some non-specific symptoms. Whether these features can be an indirect and unspecific consequence of the pulmonary disease or a generalized inflammatory state on the CNS remains to be determined; also, they may rather reflect direct SARS-CoV-2-related neuronal damage. Hematogenous versus transsynaptic propagation, the role of the angiotensin II converting enzyme receptor-2, the spread across the blood-brain barrier, the impact of the hyperimmune response (the so-called "cytokine storm"), and the possibility of virus persistence within some CNS resident cells are still debated. The different levels and severity of neurotropism and neurovirulence in patients with COVID-19 might be explained by a combination of viral and host factors and by their interaction. Twit Text FOAVip SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32751841 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32751841 #FOAvip English Wikipedia <ref>{{Cite pmid|32751841}}</ref> SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms #MMPMID32751841 Pennisi M; Lanza G; Falzone L; Fisicaro F; Ferri R; Bella R Int J Mol Sci 2020[Jul]; 21 (15): ä PMID32751841show ga Increasing evidence suggests that Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2) can also invade the central nervous system (CNS). However, findings available on its neurological manifestations and their pathogenic mechanisms have not yet been systematically addressed. A literature search on neurological complications reported in patients with COVID-19 until June 2020 produced a total of 23 studies. Overall, these papers report that patients may exhibit a wide range of neurological manifestations, including encephalopathy, encephalitis, seizures, cerebrovascular events, acute polyneuropathy, headache, hypogeusia, and hyposmia, as well as some non-specific symptoms. Whether these features can be an indirect and unspecific consequence of the pulmonary disease or a generalized inflammatory state on the CNS remains to be determined; also, they may rather reflect direct SARS-CoV-2-related neuronal damage. Hematogenous versus transsynaptic propagation, the role of the angiotensin II converting enzyme receptor-2, the spread across the blood-brain barrier, the impact of the hyperimmune response (the so-called "cytokine storm"), and the possibility of virus persistence within some CNS resident cells are still debated. The different levels and severity of neurotropism and neurovirulence in patients with COVID-19 might be explained by a combination of viral and host factors and by their interaction. |Angiotensin-Converting Enzyme 2[MESH] |Animals[MESH] |Betacoronavirus/isolation & purification/*physiology[MESH] |Blood-Brain Barrier/metabolism/virology[MESH] |Brain Diseases/complications/pathology[MESH] |COVID-19[MESH] |Central Nervous System/metabolism/*virology[MESH] |Coronavirus Infections/*pathology/virology[MESH] |Encephalitis/complications/pathology[MESH] |Humans[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/metabolism[MESH] |Pneumonia, Viral/*pathology/virology[MESH]SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular(epmc).pdf DeepDyve Pubget Overpricing