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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 IEEE+J+Biomed+Health+Inform 2021 ; 25 (4): 1326-1332 Nephropedia Template TP
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Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population #MMPMID32750959
Giamberardino PD; Iacoviello D; Papa F; Sinisgalli C
IEEE J Biomed Health Inform 2021[Apr]; 25 (4): 1326-1332 PMID32750959show ga
The present work deals with an Ordinary Differential Equation (ODE) model specifically designed to describe the COVID-19 evolution in Italy. The model is particularised on the basis of National data about the infection status of the Italian population to obtain numerical solutions that effectively reproduce the real data. Our epidemic model is a classical SEIR model that incorporates two compartments of infected subpopulations, representing diagnosed and undiagnosed individuals respectively, and an additional quarantine compartment. Possible control actions representing social, political, and medical interventions are also included. The numerical results of the proposed model identification by least square fitting are analysed and commented with special emphasis on the estimation of the number of asymptomatic infective individuals. Our fitting results are in good agreement with the epidemiological data. Short and long-term predictions on the evolution of the disease are also given.