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10.1016/j.humpath.2020.07.023

http://scihub22266oqcxt.onion/10.1016/j.humpath.2020.07.023
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32750378!7395947!32750378
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suck abstract from ncbi


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pmid32750378      Hum+Pathol 2020 ; 105 (ä): 74-83
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  • A review of the main histopathological findings in coronavirus disease 2019 #MMPMID32750378
  • Vasquez-Bonilla WO; Orozco R; Argueta V; Sierra M; Zambrano LI; Munoz-Lara F; Lopez-Molina DS; Arteaga-Livias K; Grimes Z; Bryce C; Paniz-Mondolfi A; Rodriguez-Morales AJ
  • Hum Pathol 2020[Nov]; 105 (ä): 74-83 PMID32750378show ga
  • Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, has been declared by the World Health Organization as an emerging public health problem of global importance and classified as a pandemic. SARS-CoV-2 infection can result in diverse, multiorgan pathology, the most significant being in the lungs (diffuse alveolar damage in its different phases, microthrombi, bronchopneumonia, necrotizing bronchiolitis, viral pneumonia), heart (lymphocytic myocarditis), kidney (acute tubular injury), central nervous system (microthrombi, ischemic necrosis, acute hemorrhagic infarction, congestion, and vascular edema), lymph nodes (hemophagocytosis and histiocytosis), bone marrow (hemophagocytosis), and vasculature (deep vein thrombosis). An understanding of the spectrum and frequency of histologic findings in COVID-19 is essential for gaining a better understanding of disease pathophysiology and its ongoing impact on public health. To this end, we conducted a systematic meta-analysis of histopathologic observations to date and review the reported findings.
  • |*SARS-CoV-2[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Autopsy[MESH]
  • |Biopsy[MESH]
  • |Blood Vessels/pathology[MESH]
  • |COVID-19/*pathology[MESH]
  • |Central Nervous System/pathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Kidney/pathology[MESH]
  • |Lung/pathology[MESH]
  • |Lymph Nodes/pathology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Myocardium/pathology[MESH]


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