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10.1615/CritRevImmunol.2020034441 http://scihub22266oqcxt.onion/10.1615/CritRevImmunol.2020034441 32749094!ä!32749094 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Crit+Rev+Immunol 2020 ; 40 (2): 167-171 Nephropedia Template TP {{tp|p=32749094|t=2020. Novel Coronavirus SARS-CoV-2 Target and Disable Natural Killer Cells: Core Immune Effectors for Fighting the Disease |pdf=|usr=}}{{32749094}} gab.com Text Novel Coronavirus SARS-CoV-2 Target and Disable Natural Killer Cells: Core Immune Effectors for Fighting the Disease JO: Crit Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32749094 #FOAvip Coronavirus disease 2019 (COVID-19) poses a great public health challenge worldwide. While studies on the effects of SARS-CoV-2 on immune cell function continue to progress, we know very little about the significance of depletion of key immune effectors by the virus in the mortality and morbidity of the disease. This commentary reviews what is known thus far about the effects of the virus on natural killer (NK) cells, the major cell type responsible for the destruction and removal of virally infected cells. It also highlights the necessity of comprehensive studies of NK cells in COVID-19 patients and animal models to better understand the role and significance of reported NK depletion and functional inactivation in disease morbidity and mortality, in the hopes of designing effective therapeutic interventions for the disease. Twit Text FOAVip Novel Coronavirus SARS-CoV-2 Target and Disable Natural Killer Cells: Core Immune Effectors for Fighting the Disease ????Crit Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32749094 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32749094 #FOAvip English Wikipedia <ref>{{Cite pmid|32749094}}</ref> Novel Coronavirus SARS-CoV-2 Target and Disable Natural Killer Cells: Core Immune Effectors for Fighting the Disease #MMPMID32749094 Jewett A Crit Rev Immunol 2020[]; 40 (2): 167-171 PMID32749094show ga Coronavirus disease 2019 (COVID-19) poses a great public health challenge worldwide. While studies on the effects of SARS-CoV-2 on immune cell function continue to progress, we know very little about the significance of depletion of key immune effectors by the virus in the mortality and morbidity of the disease. This commentary reviews what is known thus far about the effects of the virus on natural killer (NK) cells, the major cell type responsible for the destruction and removal of virally infected cells. It also highlights the necessity of comprehensive studies of NK cells in COVID-19 patients and animal models to better understand the role and significance of reported NK depletion and functional inactivation in disease morbidity and mortality, in the hopes of designing effective therapeutic interventions for the disease. |Antibody-Dependent Cell Cytotoxicity/immunology[MESH] |Betacoronavirus/immunology[MESH] |CD8-Positive T-Lymphocytes/immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/immunology/*pathology/therapy[MESH] |Humans[MESH] |Interferon-gamma/immunology[MESH] |Killer Cells, Natural/*immunology/*virology[MESH] |Neutrophils/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/immunology/*pathology/therapy[MESH] |SARS-CoV-2[MESH]Novel Coronavirus SARS-CoV-2 Target and Disable Natural Killer Cells: (epmc).pdf DeepDyve Pubget Overpricing