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10.1186/s40001-020-00432-3 http://scihub22266oqcxt.onion/10.1186/s40001-020-00432-3 32746929!7396942!32746929     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Med+Res 2020 ; 25 (1): 30 Nephropedia Template TP {{tp|p=32746929|t=2020. Laboratory features of severe vs non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis |pdf=|usr=}}{{32746929}} gab.com Text Laboratory features of severe vs non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis JO: Eur J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=32746929 #FOAvip BACKGROUND: More severe cases of COVID- 19 are more likely to be hospitalized and around one-fifth, needing ICU admission. Understanding the common laboratory features of COVID-19 in more severe cases versus non-severe patients could be quite useful for clinicians and might help to predict the model of disease progression. This systematic review and meta-analysis aimed to compare the laboratory test findings in severe vs. non-severe confirmed infected cases of COVID-19. METHODS: Electronic databases were systematically searched in PubMed, EMBASE, Scopus, Web of Science, and Google Scholar from the beginning of 2019 to 3rd of March 2020. Heterogeneity across included studies was determined using Cochrane's Q test and the I(2) statistic. We used the fixed or random-effect models to pool the weighted mean differences (WMDs) or standardized mean differences and 95% confidence intervals (CIs). FINDINGS: Out of a total of 3009 citations, 17 articles (22 studies, 21 from China and one study from Singapore) with 3396 ranging from 12 to1099 patients were included. Our meta-analyses showed a significant decrease in lymphocyte, monocyte, and eosinophil, hemoglobin, platelet, albumin, serum sodium, lymphocyte to C-reactive protein ratio (LCR), leukocyte to C-reactive protein ratio (LeCR), leukocyte to IL-6 ratio (LeIR), and an increase in the neutrophil, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, blood urea nitrogen (BUN), creatinine (Cr), erythrocyte Sedimentation Rate (ESR), C-reactive protein (CRP), Procalcitonin (PCT), lactate dehydrogenase (LDH), fibrinogen, prothrombin time (PT), D-dimer, glucose level, and neutrophil to lymphocyte ratio (NLR) in the severe group compared with the non-severe group. No significant changes in white blood cells (WBC), Creatine Kinase (CK), troponin I, myoglobin, IL-6 and K between the two groups were observed. INTERPRETATION: This meta-analysis provides evidence for the differentiation of severe cases of COVID-19 based on laboratory test results at the time of ICU admission. Future well-methodologically designed studies from other populations are strongly recommended. Twit Text FOAVip Laboratory features of severe vs non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis ????Eur J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=32746929 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32746929 #FOAvip English Wikipedia <ref>{{Cite pmid|32746929}}</ref> Laboratory features of severe vs non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis #MMPMID32746929 Ghahramani S; Tabrizi R; Lankarani KB; Kashani SMA; Rezaei S; Zeidi N; Akbari M; Heydari ST; Akbari H; Nowrouzi-Sohrabi P; Ahmadizar F Eur J Med Res 2020[Aug]; 25 (1): 30 PMID32746929show ga BACKGROUND: More severe cases of COVID- 19 are more likely to be hospitalized and around one-fifth, needing ICU admission. Understanding the common laboratory features of COVID-19 in more severe cases versus non-severe patients could be quite useful for clinicians and might help to predict the model of disease progression. This systematic review and meta-analysis aimed to compare the laboratory test findings in severe vs. non-severe confirmed infected cases of COVID-19. METHODS: Electronic databases were systematically searched in PubMed, EMBASE, Scopus, Web of Science, and Google Scholar from the beginning of 2019 to 3rd of March 2020. Heterogeneity across included studies was determined using Cochrane's Q test and the I(2) statistic. We used the fixed or random-effect models to pool the weighted mean differences (WMDs) or standardized mean differences and 95% confidence intervals (CIs). FINDINGS: Out of a total of 3009 citations, 17 articles (22 studies, 21 from China and one study from Singapore) with 3396 ranging from 12 to1099 patients were included. Our meta-analyses showed a significant decrease in lymphocyte, monocyte, and eosinophil, hemoglobin, platelet, albumin, serum sodium, lymphocyte to C-reactive protein ratio (LCR), leukocyte to C-reactive protein ratio (LeCR), leukocyte to IL-6 ratio (LeIR), and an increase in the neutrophil, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, blood urea nitrogen (BUN), creatinine (Cr), erythrocyte Sedimentation Rate (ESR), C-reactive protein (CRP), Procalcitonin (PCT), lactate dehydrogenase (LDH), fibrinogen, prothrombin time (PT), D-dimer, glucose level, and neutrophil to lymphocyte ratio (NLR) in the severe group compared with the non-severe group. No significant changes in white blood cells (WBC), Creatine Kinase (CK), troponin I, myoglobin, IL-6 and K between the two groups were observed. INTERPRETATION: This meta-analysis provides evidence for the differentiation of severe cases of COVID-19 based on laboratory test results at the time of ICU admission. Future well-methodologically designed studies from other populations are strongly recommended. |Asia[MESH] |Asian People[MESH] |Betacoronavirus[MESH] |Blood Coagulation[MESH] |Blood Glucose/analysis[MESH] |Blood Sedimentation[MESH] |C-Reactive Protein/analysis[MESH] |COVID-19[MESH] |China[MESH] |Clinical Laboratory Techniques[MESH] |Coronavirus Infections/*blood/*diagnosis/epidemiology[MESH] |Disease Progression[MESH] |Fibrin Fibrinogen Degradation Products/analysis[MESH] |Hospitalization[MESH] |Humans[MESH] |Inflammation[MESH] |Interleukin-6/blood[MESH] |L-Lactate Dehydrogenase/blood[MESH] |Lymphocytes/cytology[MESH] |Neutrophils/cytology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*blood/*diagnosis/epidemiology[MESH] |SARS-CoV-2[MESH] |Singapore[MESH] |Treatment Outcome[MESH]Laboratory features of severe vs non-severe COVID-19 patients in Asia(epmc).pdf DeepDyve Pubget Overpricing