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10.1186/s12879-020-05274-2

http://scihub22266oqcxt.onion/10.1186/s12879-020-05274-2
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32746801!7396931!32746801
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suck abstract from ncbi


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pmid32746801      BMC+Infect+Dis 2020 ; 20 (1): 564
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  • Clinical features and outcomes of pregnant women with COVID-19: a systematic review and meta-analysis #MMPMID32746801
  • Gao YJ; Ye L; Zhang JS; Yin YX; Liu M; Yu HB; Zhou R
  • BMC Infect Dis 2020[Aug]; 20 (1): 564 PMID32746801show ga
  • BACKGROUND: The recent COVID-19 outbreak in Wuhan, China, has quickly spread throughout the world. In this study, we systematically reviewed the clinical features and outcomes of pregnant women with COVID-19. METHODS: PubMed, Web of Science, EMBASE and MEDLINE were searched from January 1, 2020, to April 16, 2020. Case reports and case series of pregnant women infected with SARS-CoV-2 were included. Two reviewers screened 366 studies and 14 studies were included. Four reviewers independently extracted the features from the studies. We used a random-effects model to analyse the incidence (P) and 95% confidence interval (95% CI). Heterogeneity was assessed using the I(2) statistic. RESULTS: The meta-analysis included 236 pregnant women with COVID-19. The results were as follows: positive CT findings (71%; 95% CI, 0.49-0.93), caesarean section (65%; 95% CI, 0.42-0.87), fever (51%; 95% CI, 0.35-0.67), lymphopenia (49%; 95% CI, 0.29-0.70), coexisting disorders (33%; 95% CI, 0.21-0.44), cough (31%; 95% CI, 0.23-0.39), fetal distress (29%; 95% CI, 0.08-0.49), preterm labor (23%; 95% CI, 0.14-0.32), and severe case or death (12%; 95% CI, 0.03-0.20). The subgroup analysis showed that compared with non-pregnant patients, pregnant women with COVID-19 had significantly lower incidences of fever (pregnant women, 51%; non-pregnant patients, 91%; P < 0.00001) and cough (pregnant women, 31%; non-pregnant patients, 67%; P < 0.0001). CONCLUSIONS: The incidences of fever, cough and positive CT findings in pregnant women with COVID-19 are less than those in the normal population with COVID-19, but the rate of preterm labor is higher among pregnant with COVID-19 than among normal pregnant women. There is currently no evidence that COVID-19 can spread through vertical transmission.
  • |*Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Cesarean Section[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/diagnostic imaging/*epidemiology/virology[MESH]
  • |Cough/epidemiology/virology[MESH]
  • |Female[MESH]
  • |Fever/epidemiology/virology[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Infant, Newborn[MESH]
  • |Infectious Disease Transmission, Vertical[MESH]
  • |Obstetric Labor, Premature/*epidemiology/virology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnostic imaging/*epidemiology/virology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/diagnostic imaging/*epidemiology/virology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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