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10.1080/17512433.2020.1805315

http://scihub22266oqcxt.onion/10.1080/17512433.2020.1805315
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32746653!ä!32746653

suck abstract from ncbi


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pmid32746653      Expert+Rev+Clin+Pharmacol 2020 ; 13 (9): 957-975
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  • Medication therapy strategies for the coronavirus disease 2019 (COVID-19): recent progress and challenges #MMPMID32746653
  • Yang X; Liu Y; Liu Y; Yang Q; Wu X; Huang X; Liu H; Cai W; Ma G
  • Expert Rev Clin Pharmacol 2020[Sep]; 13 (9): 957-975 PMID32746653show ga
  • INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and identify effective medication therapy strategies to combat the COVID-19. AREAS COVERED: Here, we summarized and evaluated the current treatment drugs and regimens, and put forward the treatment recommendations, including using the potential repurposed or experimental drugs against COVID-19, e.g. chloroquine (CQ), hydroxychloroquine (HCQ), lopinavir/ritonavir (LPV/r), remdesivir (RDV), and favipiravir (FPV). We also analyzed the specific drugs and vaccines against SARS-CoV-2 ongoing development and formulated the comprehensive treatment regimens based on condition of patients, diseases and drugs as well as concomitant medications. EXPERT OPINION: No drugs and vaccines have been proven to be particularly effective against SARS-CoV-2 up to now. The recommended comprehensive medication therapy strategies have already displayed favorable effect in the fight against COVID-19. Research should be focused on the development of anti-SARS-CoV-2 drugs and vaccines based on high-quality clinical trial evidence, treatment guidelines and expert consensus.
  • |*Betacoronavirus/drug effects[MESH]
  • |*Viral Vaccines[MESH]
  • |Antiviral Agents/administration & dosage/adverse effects/pharmacology/*therapeutic use[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Coronavirus Infections/*drug therapy/epidemiology/*prevention & control[MESH]
  • |Global Health[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/*drug therapy/epidemiology/*prevention & control[MESH]


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