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Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 IEEE+Trans+Ultrason+Ferroelectr+Freq+Control 2020 ; 67 (11): 2258-2264 Nephropedia Template TP
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In Vivo Assessment of Lung Ultrasound Features Mimicking Viral Pneumonia Using a Large Animal Model #MMPMID32746213
Wolfram F; Braun C; Gutsche H; Lesser TG
IEEE Trans Ultrason Ferroelectr Freq Control 2020[Nov]; 67 (11): 2258-2264 PMID32746213show ga
Lung ultrasound (LUS) is a practical tool for lung diagnosis when computer tomography (CT) is not available. Recent findings suggest that LUS diagnosis is highly advantageous because of its mobility and correlation with radiological findings for viral pneumonia. Simple models for both educational evaluation and technical evaluation are needed. Therefore, this work investigates the usability of a large animal model under aspects of LUS features of viral pneumonia using saline one lung flooding. Six pigs were intubated with a double-lumen tube, and the left lung was instilled with saline. During the instillation of up to 12.5 ml/kg, the sonographic features were assessed. All features present during viral pneumonia were found, such as B-lines, white lung syndrome, pleural thickening, and the formation of pleural consolidations. Sonographic findings correlate well with current LUS scores for COVID19. The scores of 1, 2, and 3 were dominantly present at 1-4-, 4-8-, and 8-12-ml/kg saline instillation, respectively. The noninfective animal model can be used for further investigation of the LUS features and can serve in education, by helping with the appropriate handling of LUS in clinical practice during management of viral pneumonia.