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Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Jpn+J+Infect+Dis 2021 ; 74 (1): 54-60 Nephropedia Template TP
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Predictors of Coronavirus Disease 2019 Severity: A Retrospective Study of 64 Cases #MMPMID32741931
Huang H; Song B; Xu Z; Jiao Y; Huang L; Zhao P; Huang J; Zhou Z; Zhao Z; Tian J; Zhou Y; Wang FS; Jiang T
Jpn J Infect Dis 2021[Jan]; 74 (1): 54-60 PMID32741931show ga
This study aimed to analyze the clinical characteristics and potential predictors of disease severity in patients with coronavirus disease 2019 (COVID-19). We retrospectively analyzed the clinical data from 64 (37 male and 27 female) patients with COVID-19. Their mean age was 47.8 years; 43 (67.2%) cases were non-severe, 21 (32.8%) were severe, and 2 patients (3.1%) died. Age and serum ferritin levels were significantly associated with COVID-19 severity. There were no significant differences in the duration of severe illness or the number of days on high-level respiratory support between the low-dose and high-dose methylprednisolone groups. The mean number of days in hospital in the high-dose group was higher than that in the low-dose group. Repeated monitoring of ferritin, interleukin-6, C-reactive protein, lactic acid dehydrogenase, and erythrocyte sedimentation rate during COVID-19 treatment may assist in the prediction of disease severity and evaluation of treatment effects.