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10.1016/j.phymed.2020.153286 http://scihub22266oqcxt.onion/10.1016/j.phymed.2020.153286 32741697!7367004!32741697     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32741697&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Phytomedicine 2021 ; 85 (?): 153286 Nephropedia Template TP {{tp|p=32741697|t=2021. Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review |pdf=|usr=}}{{32741697}} gab.com Text Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review JO: Phytomedicine http://www.kidney.de/pget.php?&tw=1&pmid=32741697 #FOAvip BACKGROUND: The rapid spread of novel coronavirus called SARS-CoV-2 or nCoV has caused countries all over the world to impose lockdowns and undertake stringent preventive measures. This new positive-sense single-stranded RNA strain of coronavirus spreads through droplets of saliva and nasal discharge. PURPOSE: US FDA has authorized the emergency use of Remdesivir looking at the increasing number of cases of COVID-19, however there is still no drug approved to treat COVID-19. An alternative way of treatment could be the use of naturally derived molecules with known antiviral properties. METHOD: We reviewed the antiviral activities of two polyphenols derived from tea, epigallocatechin-3-gallate (EGCG) from green tea and theaflavins from black tea. Both green tea and black tea polyphenols have been reported to exhibit antiviral activities against various viruses, especially positive-sense single-stranded RNA viruses. RESULTS: Recent studies have revealed the possible binding sites present on SARS-CoV-2 and studied their interactions with tea polyphenols. EGCG and theaflavins, especially theaflavin-3,3'-digallate (TF3) have shown a significant interaction with the receptors under consideration in this review. Some docking studies further emphasize on the activity of these polyphenols against COVID-19. CONCLUSION: This review summarizes the available reports and evidences which support the use of tea polyphenols as potential candidates in prophylaxis and treatment of COVID-19. Twit Text FOAVip Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review ????Phytomedicine http://www.kidney.de/pget.php?&tw=1&pmid=32741697 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32741697 #FOAvip English Wikipedia <ref>{{Cite pmid|32741697}}</ref> Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review #MMPMID32741697 Mhatre S; Srivastava T; Naik S; Patravale V Phytomedicine 2021[May]; 85 (?): 153286 PMID32741697show ga BACKGROUND: The rapid spread of novel coronavirus called SARS-CoV-2 or nCoV has caused countries all over the world to impose lockdowns and undertake stringent preventive measures. This new positive-sense single-stranded RNA strain of coronavirus spreads through droplets of saliva and nasal discharge. PURPOSE: US FDA has authorized the emergency use of Remdesivir looking at the increasing number of cases of COVID-19, however there is still no drug approved to treat COVID-19. An alternative way of treatment could be the use of naturally derived molecules with known antiviral properties. METHOD: We reviewed the antiviral activities of two polyphenols derived from tea, epigallocatechin-3-gallate (EGCG) from green tea and theaflavins from black tea. Both green tea and black tea polyphenols have been reported to exhibit antiviral activities against various viruses, especially positive-sense single-stranded RNA viruses. RESULTS: Recent studies have revealed the possible binding sites present on SARS-CoV-2 and studied their interactions with tea polyphenols. EGCG and theaflavins, especially theaflavin-3,3'-digallate (TF3) have shown a significant interaction with the receptors under consideration in this review. Some docking studies further emphasize on the activity of these polyphenols against COVID-19. CONCLUSION: This review summarizes the available reports and evidences which support the use of tea polyphenols as potential candidates in prophylaxis and treatment of COVID-19. |*COVID-19 Drug Treatment[MESH] |Antioxidants/pharmacology[MESH] |Antiviral Agents/*pharmacology[MESH] |Biflavonoids/pharmacology[MESH] |Binding Sites[MESH] |Camellia sinensis/chemistry[MESH] |Catechin/analogs & derivatives/pharmacology[MESH] |Humans[MESH] |Polyphenols/*pharmacology[MESH] |SARS-CoV-2/*drug effects[MESH]Antiviral activity of green tea and black tea polyphenols in prophylax(epmc).pdf DeepDyve Pubget Overpricing