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10.1016/j.nut.2020.110900 http://scihub22266oqcxt.onion/10.1016/j.nut.2020.110900 32738510!7836308!32738510     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nutrition 2021 ; 81 (ä): 110900 Nephropedia Template TP {{tp|p=32738510|t=2021. Parenteral fish oil: An adjuvant pharmacotherapy for coronavirus disease 2019?|pdf=|usr=}}{{32738510}} gab.com Text Parenteral fish oil: An adjuvant pharmacotherapy for coronavirus disease 2019 JO: Nutrition http://www.kidney.de/pget.php?&tw=1&pmid=32738510 #FOAvip The new coronavirus associated with severe acute respiratory syndrome (SARS-CoV-2), surprisingly, does not affect only the lungs. The severe response to SARS-CoV-2 appears to include a "cytokine storm," which indicates a state of hyperinflammation and subsequent dysfunction of multiple organs and tissues in the most severe cases. This could be the reason why populations at the highest risk for death from the SARS-CoV-2 infection-induced disease (coronavirus disease 2019 [COVID-19]) are those suffering from chronic low-grade inflammation, but prone to hyperinflammation. This includes individuals of advanced age and those with obesity, type 2 diabetes, hypertension, and metabolic syndrome. Inflammation resolution is strongly dependent on lipid mediators, the specialized pro-resolution mediators (SPMs). omega-3 polyunsaturated fatty acids (omega-3 PUFAs) are precursors of very potent SPMs, including resolvins, protectins, and maresins. Additionally, they are associated with a less aggressive inflammatory initiation, after competing with omega-6 fatty acids for eicosanoid synthesis. Therefore, it makes sense to consider the use of omega-3 PUFAs for clinical management of COVID-19 patients. omega-3 PUFAs may be given by oral, enteral, or parenteral routes; however, the parenteral route favors faster incorporation into plasma phospholipids, blood cells, and tissues. Here, we discuss these aspects to propose the parenteral infusion of omega-3 PUFAs as adjuvant immunopharmacotherapy for hospitalized patients with COVID-19. Twit Text FOAVip Parenteral fish oil: An adjuvant pharmacotherapy for coronavirus disease 2019 ????Nutrition http://www.kidney.de/pget.php?&tw=1&pmid=32738510 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32738510 #FOAvip English Wikipedia <ref>{{Cite pmid|32738510}}</ref> Parenteral fish oil: An adjuvant pharmacotherapy for coronavirus disease 2019? #MMPMID32738510 Torrinhas RS; Calder PC; Lemos GO; Waitzberg DL Nutrition 2021[Jan]; 81 (ä): 110900 PMID32738510show ga The new coronavirus associated with severe acute respiratory syndrome (SARS-CoV-2), surprisingly, does not affect only the lungs. The severe response to SARS-CoV-2 appears to include a "cytokine storm," which indicates a state of hyperinflammation and subsequent dysfunction of multiple organs and tissues in the most severe cases. This could be the reason why populations at the highest risk for death from the SARS-CoV-2 infection-induced disease (coronavirus disease 2019 [COVID-19]) are those suffering from chronic low-grade inflammation, but prone to hyperinflammation. This includes individuals of advanced age and those with obesity, type 2 diabetes, hypertension, and metabolic syndrome. Inflammation resolution is strongly dependent on lipid mediators, the specialized pro-resolution mediators (SPMs). omega-3 polyunsaturated fatty acids (omega-3 PUFAs) are precursors of very potent SPMs, including resolvins, protectins, and maresins. Additionally, they are associated with a less aggressive inflammatory initiation, after competing with omega-6 fatty acids for eicosanoid synthesis. Therefore, it makes sense to consider the use of omega-3 PUFAs for clinical management of COVID-19 patients. omega-3 PUFAs may be given by oral, enteral, or parenteral routes; however, the parenteral route favors faster incorporation into plasma phospholipids, blood cells, and tissues. Here, we discuss these aspects to propose the parenteral infusion of omega-3 PUFAs as adjuvant immunopharmacotherapy for hospitalized patients with COVID-19. |*COVID-19 Drug Treatment[MESH] |COVID-19/epidemiology/immunology[MESH] |Chemotherapy, Adjuvant[MESH] |Cytokine Release Syndrome/drug therapy/immunology[MESH] |Fatty Acids, Omega-3/administration & dosage[MESH] |Fish Oils/*administration & dosage[MESH] |Humans[MESH] |Inflammation/diet therapy/immunology[MESH] |Infusions, Parenteral[MESH] |Models, Biological[MESH] |Nutritional Physiological Phenomena[MESH] |Pandemics[MESH]Parenteral fish oil: An adjuvant pharmacotherapy for coronavirus disea(epmc).pdf DeepDyve Pubget Overpricing