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10.1016/j.diabet.2020.07.005 http://scihub22266oqcxt.onion/10.1016/j.diabet.2020.07.005 32738402!7388778!32738402     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diabetes+Metab 2021 ; 47 (2): 101178 Nephropedia Template TP {{tp|p=32738402|t=2021. Body mass index and outcome in patients with COVID-19: A dose-response meta-analysis |pdf=|usr=}}{{32738402}} gab.com Text Body mass index and outcome in patients with COVID-19: A dose-response meta-analysis JO: Diabetes Metab http://www.kidney.de/pget.php?&tw=1&pmid=32738402 #FOAvip BACKGROUND: There is mounting evidence related to the association between obesity and severity of COVID-19. However, the direct relationship of the increase in the severe COVID-19 risk factors, with an increase in body mass index (BMI), has not yet been evaluated. AIM: This meta-analysis aims to evaluate the dose-response relationship between body mass index (BMI) and poor outcome in patients with COVID-19. METHODS: A systematic literature search was conducted using PubMed, Europe PMC, ProQuest, and the Cochrane Central Database. The primary outcome was composite poor outcome composed of mortality and severity. The secondary outcomes were mortality and severity. RESULTS: A total of 34,390 patients from 12 studies were included in this meta-analysis. The meta-analysis demonstrated that obesity was associated with composite poor outcome (OR 1.73 [1.40, 2.14], P<0.001; I(2): 55.6%), mortality (OR 1.55 [1.16, 2.06], P=0.003; I(2): 74.4%), and severity (OR 1.90 [1.45, 2.48], P<0.001; I(2): 5.2%) in patients with COVID-19. A pooled analysis of highest BMI versus reference BMI indicate that a higher BMI in the patients was associated with composite poor outcome (aOR 3.02 [1.82, 5.00], P<0.001; I(2): 59.8%), mortality (aOR 2.85 [1.17, 6.92], P=0.002; I(2): 79.7%), and severity (aOR 3.08 [1.78, 5.33], P<0.001; I(2): 11.7%). The dose-response meta-analysis showed an increased risk of composite poor outcome by aOR of 1.052 [1.028, 1.077], P<0.001 for every 5kg/m(2) increase in BMI (P(non-linearity)<0.001). The curve became steeper with increasing BMI. CONCLUSION: Dose-response meta-analysis demonstrated that increased BMI was associated with increased poor outcome in patients with COVID-19. Twit Text FOAVip Body mass index and outcome in patients with COVID-19: A dose-response meta-analysis ????Diabetes Metab http://www.kidney.de/pget.php?&tw=1&pmid=32738402 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32738402 #FOAvip English Wikipedia <ref>{{Cite pmid|32738402}}</ref> Body mass index and outcome in patients with COVID-19: A dose-response meta-analysis #MMPMID32738402 Pranata R; Lim MA; Yonas E; Vania R; Lukito AA; Siswanto BB; Meyer M Diabetes Metab 2021[Mar]; 47 (2): 101178 PMID32738402show ga BACKGROUND: There is mounting evidence related to the association between obesity and severity of COVID-19. However, the direct relationship of the increase in the severe COVID-19 risk factors, with an increase in body mass index (BMI), has not yet been evaluated. AIM: This meta-analysis aims to evaluate the dose-response relationship between body mass index (BMI) and poor outcome in patients with COVID-19. METHODS: A systematic literature search was conducted using PubMed, Europe PMC, ProQuest, and the Cochrane Central Database. The primary outcome was composite poor outcome composed of mortality and severity. The secondary outcomes were mortality and severity. RESULTS: A total of 34,390 patients from 12 studies were included in this meta-analysis. The meta-analysis demonstrated that obesity was associated with composite poor outcome (OR 1.73 [1.40, 2.14], P<0.001; I(2): 55.6%), mortality (OR 1.55 [1.16, 2.06], P=0.003; I(2): 74.4%), and severity (OR 1.90 [1.45, 2.48], P<0.001; I(2): 5.2%) in patients with COVID-19. A pooled analysis of highest BMI versus reference BMI indicate that a higher BMI in the patients was associated with composite poor outcome (aOR 3.02 [1.82, 5.00], P<0.001; I(2): 59.8%), mortality (aOR 2.85 [1.17, 6.92], P=0.002; I(2): 79.7%), and severity (aOR 3.08 [1.78, 5.33], P<0.001; I(2): 11.7%). The dose-response meta-analysis showed an increased risk of composite poor outcome by aOR of 1.052 [1.028, 1.077], P<0.001 for every 5kg/m(2) increase in BMI (P(non-linearity)<0.001). The curve became steeper with increasing BMI. CONCLUSION: Dose-response meta-analysis demonstrated that increased BMI was associated with increased poor outcome in patients with COVID-19. |Aged[MESH] |Body Mass Index[MESH] |COVID-19/complications/*therapy[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Obesity/*complications[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]Body mass index and outcome in patients with COVID-19: A dose-response(epmc).pdf DeepDyve Pubget Overpricing