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10.1016/j.bbi.2020.07.037 http://scihub22266oqcxt.onion/10.1016/j.bbi.2020.07.037 32738287!7390748!32738287     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Brain+Behav+Immun 2020 ; 89 (ä): 594-600 Nephropedia Template TP {{tp|p=32738287|t=2020. Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors |pdf=|usr=}}{{32738287}} gab.com Text Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors JO: Brain Behav Immun http://www.kidney.de/pget.php?&tw=1&pmid=32738287 #FOAvip Infection-triggered perturbation of the immune system could induce psychopathology, and psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) pandemic could be associated with psychiatric implications. We investigated the psychopathological impact of COVID-19 in survivors, also considering the effect of clinical and inflammatory predictors. We screened for psychiatric symptoms 402 adults surviving COVID-19 (265 male, mean age 58), at one month follow-up after hospital treatment. A clinical interview and a battery of self-report questionnaires were used to investigate post-traumatic stress disorder (PTSD), depression, anxiety, insomnia, and obsessive-compulsive (OC) symptomatology. We collected sociodemographic information, clinical data, baseline inflammatory markers and follow-up oxygen saturation levels. A significant proportion of patients self-rated in the psychopathological range: 28% for PTSD, 31% for depression, 42% for anxiety, 20% for OC symptoms, and 40% for insomnia. Overall, 56% scored in the pathological range in at least one clinical dimension. Despite significantly lower levels of baseline inflammatory markers, females suffered more for both anxiety and depression. Patients with a positive previous psychiatric diagnosis showed increased scores on most psychopathological measures, with similar baseline inflammation. Baseline systemic immune-inflammation index (SII), which reflects the immune response and systemic inflammation based on peripheral lymphocyte, neutrophil, and platelet counts, positively associated with scores of depression and anxiety at follow-up. PTSD, major depression, and anxiety, are all high-burden non-communicable conditions associated with years of life lived with disability. Considering the alarming impact of COVID-19 infection on mental health, the current insights on inflammation in psychiatry, and the present observation of worse inflammation leading to worse depression, we recommend to assess psychopathology of COVID-19 survivors and to deepen research on inflammatory biomarkers, in order to diagnose and treat emergent psychiatric conditions. Twit Text FOAVip Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors ????Brain Behav Immun http://www.kidney.de/pget.php?&tw=1&pmid=32738287 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32738287 #FOAvip English Wikipedia <ref>{{Cite pmid|32738287}}</ref> Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors #MMPMID32738287 Mazza MG; De Lorenzo R; Conte C; Poletti S; Vai B; Bollettini I; Melloni EMT; Furlan R; Ciceri F; Rovere-Querini P; Benedetti F Brain Behav Immun 2020[Oct]; 89 (ä): 594-600 PMID32738287show ga Infection-triggered perturbation of the immune system could induce psychopathology, and psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) pandemic could be associated with psychiatric implications. We investigated the psychopathological impact of COVID-19 in survivors, also considering the effect of clinical and inflammatory predictors. We screened for psychiatric symptoms 402 adults surviving COVID-19 (265 male, mean age 58), at one month follow-up after hospital treatment. A clinical interview and a battery of self-report questionnaires were used to investigate post-traumatic stress disorder (PTSD), depression, anxiety, insomnia, and obsessive-compulsive (OC) symptomatology. We collected sociodemographic information, clinical data, baseline inflammatory markers and follow-up oxygen saturation levels. A significant proportion of patients self-rated in the psychopathological range: 28% for PTSD, 31% for depression, 42% for anxiety, 20% for OC symptoms, and 40% for insomnia. Overall, 56% scored in the pathological range in at least one clinical dimension. Despite significantly lower levels of baseline inflammatory markers, females suffered more for both anxiety and depression. Patients with a positive previous psychiatric diagnosis showed increased scores on most psychopathological measures, with similar baseline inflammation. Baseline systemic immune-inflammation index (SII), which reflects the immune response and systemic inflammation based on peripheral lymphocyte, neutrophil, and platelet counts, positively associated with scores of depression and anxiety at follow-up. PTSD, major depression, and anxiety, are all high-burden non-communicable conditions associated with years of life lived with disability. Considering the alarming impact of COVID-19 infection on mental health, the current insights on inflammation in psychiatry, and the present observation of worse inflammation leading to worse depression, we recommend to assess psychopathology of COVID-19 survivors and to deepen research on inflammatory biomarkers, in order to diagnose and treat emergent psychiatric conditions. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Anxiety Disorders/*epidemiology/immunology/psychology[MESH] |Anxiety/epidemiology/immunology/psychology[MESH] |Betacoronavirus[MESH] |C-Reactive Protein/immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology/immunology/psychology[MESH] |Depression/epidemiology/immunology/psychology[MESH] |Depressive Disorder, Major/*epidemiology/immunology/psychology[MESH] |Depressive Disorder/epidemiology/immunology/psychology[MESH] |Emergency Service, Hospital[MESH] |Female[MESH] |Humans[MESH] |Inflammation[MESH] |Italy/epidemiology[MESH] |Length of Stay/statistics & numerical data[MESH] |Leukocyte Count[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Mental Disorders/epidemiology/immunology/psychology[MESH] |Middle Aged[MESH] |Monocytes[MESH] |Neutrophils[MESH] |Obsessive-Compulsive Disorder/epidemiology/immunology/psychology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*epidemiology/immunology/psychology[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |Sex Factors[MESH] |Sleep Initiation and Maintenance Disorders/epidemiology/immunology/psychology[MESH] |Stress Disorders, Post-Traumatic/epidemiology/immunology/psychology[MESH] |Suicidal Ideation[MESH] |Survivors/psychology/*statistics & numerical data[MESH]Anxiety and depression in COVID-19 survivors: Role of inflammatory and(epmc).pdf DeepDyve Pubget Overpricing