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10.1210/clinem/dgaa487

http://scihub22266oqcxt.onion/10.1210/clinem/dgaa487
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32738040!7454653!32738040
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suck abstract from ncbi


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pmid32738040      J+Clin+Endocrinol+Metab 2020 ; 105 (12): ä
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  • Bilateral Adrenal Hemorrhage in Coronavirus Disease 2019 Patient: A Case Report #MMPMID32738040
  • Frankel M; Feldman I; Levine M; Frank Y; Bogot NR; Benjaminov O; Kurd R; Breuer GS; Munter G
  • J Clin Endocrinol Metab 2020[Dec]; 105 (12): ä PMID32738040show ga
  • CONTEXT: Bilateral adrenal hemorrhage is a rare condition with potentially life-threatening consequences such as acute adrenal insufficiency. Early adrenal axis testing, as well as directed imaging, is crucial for immediate diagnosis and treatment. Coronavirus disease 2019 (COVID-19) has been associated with coagulopathy and thromboembolic events. CASE DESCRIPTION: A 66-year-old woman presented with acute COVID-19 infection and primary adrenal insufficiency due to bilateral adrenal hemorrhage (BAH). She also had a renal vein thrombosis. Her past medical history revealed primary antiphospholipid syndrome (APLS). Four weeks after discharge she had no signs of COVID-19 infection and her polymerase chain reaction test for COVID-19 was negative, but she still needed glucocorticoid and mineralocorticoid replacement therapy. The combination of APLS and COVID-19 was probably responsible of the adrenal event as a "two-hit" mechanism. CONCLUSIONS: COVID-19 infection is associated with coagulopathy and thromboembolic events, including BAH. Adrenal insufficiency is life threatening; therefore, we suggest that early adrenal axis testing for COVID-19 patients with clinical suspicion of adrenal insufficiency should be carried out.
  • |Adrenal Gland Diseases/*etiology/pathology[MESH]
  • |Aged[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications/virology[MESH]
  • |Female[MESH]
  • |Hemorrhage/*etiology/pathology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/virology[MESH]
  • |Prognosis[MESH]
  • |SARS-CoV-2[MESH]


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