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10.1016/j.jinf.2020.07.027

http://scihub22266oqcxt.onion/10.1016/j.jinf.2020.07.027
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32735893!7387283!32735893
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suck abstract from ncbi


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pmid32735893      J+Infect 2020 ; 81 (4): 621-624
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  • Increased risk of SARS-CoV-2 infection in staff working across different care homes: enhanced CoVID-19 outbreak investigations in London care Homes #MMPMID32735893
  • Ladhani SN; Chow JY; Janarthanan R; Fok J; Crawley-Boevey E; Vusirikala A; Fernandez E; Perez MS; Tang S; Dun-Campbell K; Wynne-Evans E; Bell A; Patel B; Amin-Chowdhury Z; Aiano F; Paranthaman K; Ma T; Saavedra-Campos M; Myers R; Ellis J; Lackenby A; Gopal R; Patel M; Chand M; Brown K; Hopkins S; Consortium C; Shetty N; Zambon M; Ramsay ME
  • J Infect 2020[Oct]; 81 (4): 621-624 PMID32735893show ga
  • BACKGROUND: Care homes have been disproportionately affected by the COVID-19 pandemic and continue to suffer large outbreaks even when community infection rates are declining, thus representing important pockets of transmission. We assessed occupational risk factors for SARS-CoV-2 infection among staff in six care homes experiencing a COVID-19 outbreak during the peak of the pandemic in London, England. METHODS: Care home staff were tested for SARS-COV-2 infection by RT-PCR and asked to report any symptoms, their contact with residents and if they worked in different care homes. Whole genome sequencing (WGS) was performed on RT-PCR positive samples. RESULTS: In total, 53 (21%) of 254 staff were SARS-CoV-2 positive but only 12/53 (23%) were symptomatic. Among staff working in a single care home, SARS-CoV-2 positivity was 15% (2/13), 16% (7/45) and 18% (30/169) in those reporting no, occasional and regular contact with residents. In contrast, staff working across different care homes (14/27, 52%) had a 3.0-fold (95% CI, 1.9-4.8; P<0.001) higher risk of SARS-CoV-2 positivity than staff working in single care homes (39/227, 17%). WGS identified SARS-CoV-2 clusters involving staff only, including some that included staff working across different care homes. CONCLUSIONS: SARS-CoV-2 positivity was significantly higher among staff working across different care homes than those who were working in the same care home. We found local clusters of SARS-CoV-2 infection between staff only, including those with minimal resident contact. Infection control should be extended for all contact, including those between staff, whilst on care home premises.
  • |Betacoronavirus/genetics[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology/transmission[MESH]
  • |England/epidemiology[MESH]
  • |Genome, Viral/genetics[MESH]
  • |Homes for the Aged/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Infection Control/methods[MESH]
  • |London/epidemiology[MESH]
  • |Medical Staff/*statistics & numerical data[MESH]
  • |Nursing Homes/*statistics & numerical data[MESH]
  • |Occupational Exposure/*adverse effects[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/transmission[MESH]
  • |SARS-CoV-2[MESH]


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