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10.1002/oby.22979

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32735706!7436536!32735706
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suck abstract from ncbi


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pmid32735706      Obesity+(Silver+Spring) 2020 ; 28 (11): 2049-2055
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  • Overweight and Obesity are Risk Factors of Severe Illness in Patients with COVID-19 #MMPMID32735706
  • Wang J; Zhu L; Liu L; Zhao XA; Zhang Z; Xue L; Yan X; Huang S; Li Y; Cheng J; Zhang B; Xu T; Li C; Ji F; Ming F; Zhao Y; Shao H; Sang D; Zhao H; Guan X; Chen X; Chen Y; Issa R; Wei J; Huang R; Zhu C; Wu C
  • Obesity (Silver Spring) 2020[Nov]; 28 (11): 2049-2055 PMID32735706show ga
  • OBJECTIVE: This study aimed to observe the clinical characteristics of patients with coronavirus disease 2019 (COVID-19) with overweight and obesity. METHODS: Consecutive patients with COVID-19 from 10 hospitals of Jiangsu province, China, were enrolled. RESULTS: A total of 297 patients with COVID-19 were included, and 39.39% and 13.47% of patients had overweight and obesity, respectively. The proportions of bilateral pneumonia (92.50% vs. 73.57%, P = 0.033) and type 2 diabetes (17.50% vs. 3.57%, P = 0.006) were higher in patients with obesity than lean patients. The proportions of severe illness in patients with overweight (12.82% vs. 2.86%, P = 0.006) and obesity (25.00% vs. 2.86%, P < 0.001) were significantly higher than lean patients. More patients with obesity developed respiratory failure (20.00% vs. 2.86%, P < 0.001) and acute respiratory distress syndrome (5.00% vs. 0%, P = 0.024) than lean patients. The median days of hospitalization were longer in patients with obesity than lean patients (17.00 days vs. 14.00 days, P = 0.029). Overweight (OR, 4.222; 95% CI: 1.322-13.476; P = 0.015) and obesity (OR, 9.216; 95% CI: 2.581-32.903; P = 0.001) were independent risk factors of severe illness. Obesity (HR, 6.607; 95% CI: 1.955-22.329; P = 0.002) was an independent risk factor of respiratory failure. CONCLUSIONS: Overweight and obesity were independent risk factors of severe illness in COVID-19 patients. More attention should be paid to these patients.
  • |Adult[MESH]
  • |Animals[MESH]
  • |Betacoronavirus/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Diabetes Mellitus, Type 2[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Obesity/*complications[MESH]
  • |Overweight/*complications[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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