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10.2174/1573403X16666200731162614

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suck abstract from ncbi


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pmid32735524      Curr+Cardiol+Rev 2021 ; 17 (1): 74-77
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  • The Deadly Quartet (Covid-19, Old Age, Lung Disease, and Heart Failure) Explains Why Coronavirus-Related Mortality in Northern Italy Was So High #MMPMID32735524
  • Calcaterra G; Bassareo PP; Barilla F; Sergi D; Chiocchi M; Romeo F; Mehta JL
  • Curr Cardiol Rev 2021[]; 17 (1): 74-77 PMID32735524show ga
  • Since its outbreak in China at the end of 2019, the new coronavirus disease (COVID-19) was characterized by both easy spreading and high mortality. The latter proved to be way more elevated in the North of Italy -with a peak of 18.4% in region Lombardia and even 31% in the city of Bergamo and surrounding county- than in the rest of the world. In an attempt to conceptualize the reasons for such a dramatic situation, four key elements have been identified: COVID-19 itself, old age, lung disease, and heart failure. Their harmful combination has been named "The deadly quartet". The underlying risk factors, among which a lot of them are distinctive features of the population in northern Italy, have been summarized as "unmodifiable", "partially modifiable", and "modifiable", for the sake of clarity. Up-to-date scientific evidence in this field has been described in the form of a narrative and easy-to-read review.
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |COVID-19/epidemiology/*mortality[MESH]
  • |Disease Outbreaks[MESH]
  • |Heart Failure/epidemiology/*mortality/virology[MESH]
  • |Humans[MESH]
  • |Italy/epidemiology[MESH]
  • |Lung Diseases/epidemiology/*mortality/virology[MESH]
  • |Risk Factors[MESH]


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