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10.1259/bjr.20200407

http://scihub22266oqcxt.onion/10.1259/bjr.20200407
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32735448!7465860!32735448
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suck abstract from ncbi


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pmid32735448      Br+J+Radiol 2020 ; 93 (1113): 20200407
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  • Pulmonary thromboembolism in hospitalised COVID-19 patients at moderate to high risk by Wells score: a report from Lombardy, Italy #MMPMID32735448
  • Monfardini L; Morassi M; Botti P; Stellini R; Bettari L; Pezzotti S; Ali M; Monaco CG; Magni V; Cozzi A; Schiaffino S; Bna C
  • Br J Radiol 2020[Sep]; 93 (1113): 20200407 PMID32735448show ga
  • OBJECTIVES: To present a single-centre experience on CT pulmonary angiography (CTPA) for the assessment of hospitalised COVID-19 patients with moderate-to-high risk of pulmonary thromboembolism (PTE). METHODS: We analysed consecutive COVID-19 patients (RT-PCR confirmed) undergoing CTPA in March 2020 for PTE clinical suspicion. Clinical data were retrieved. Two experienced radiologists reviewed CTPAs to assess pulmonary parenchyma and vascular findings. RESULTS: Among 34 patients who underwent CTPA, 26 had PTE (76%, 20 males, median age 61 years, interquartile range 54-70), 20/26 (77%) with comorbidities (mainly hypertension, 44%), and 8 (31%) subsequently dying. Eight PTE patients were under thromboprophylaxis with low-molecular-weight heparin, four PTE patients had lower-limbs deep vein thrombosis at ultrasound examination (performed in 33/34 patients). Bilateral PTE characterised 19/26 cases, with main branches involved in 10/26 cases. Twelve patients had a parenchymal involvement >75%, the predominant pneumonia pattern being consolidation in 10/26 patients, ground glass opacities in 9/26, crazy paving in 5/26, and both ground glass opacities and consolidation in 2/26. CONCLUSION: COVID-19 patients are prone to PTE. ADVANCES IN KNOWLEDGE: PTE, potentially attributable to an underlying thrombophilic status, may be more frequent than expected in COVID-19 patients. Extension of prophylaxis and adaptation of diagnostic criteria should be considered.
  • |*Betacoronavirus[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Computed Tomography Angiography/methods[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Inpatients/*statistics & numerical data[MESH]
  • |Italy/epidemiology[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology[MESH]
  • |Pulmonary Embolism/*epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |Risk[MESH]


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