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10.1016/j.ejogrb.2020.07.008

http://scihub22266oqcxt.onion/10.1016/j.ejogrb.2020.07.008
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32732059!7362841!32732059
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suck abstract from ncbi


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pmid32732059      Eur+J+Obstet+Gynecol+Reprod+Biol 2020 ; 252 (ä): 559-562
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  • Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study #MMPMID32732059
  • Antoun L; Taweel NE; Ahmed I; Patni S; Honest H
  • Eur J Obstet Gynecol Reprod Biol 2020[Sep]; 252 (ä): 559-562 PMID32732059show ga
  • OBJECTIVE: To study the effect of COVID-19 on pregnancy and neonatal outcomes. STUDY DESIGN: Prospective cohort study in a large tertiary maternity unit within a university hospital with an average annual birth of over 10,000 births. We prospectively collected and analysed data for a cohort of 23 pregnant patients including singleton and multiple pregnancies tested positive for COVID-19 between February 2020 and April 2020 inclusive to assess the effect of COVID-19 on pregnancy, and neonatal outcomes. RESULTS: Twenty-three pregnant patients tested positive for COVID-19, delivering 20 babies including a set of twins, with four ongoing pregnancies at the time of manuscript submission. 16/23 (70 %) whom tested positive were patients from Asian (Indian sub-continent) background. The severity of the symptoms ranged from mild in 13/23 (65.2 %) of the patients, moderate in 2/23 (8.7 %), and severe in 8/23 (34.8 %). Four out of total 23 COVID-19 pregnant patients (17.4 %) developed severe adult respiratory distress syndrome complications requiring ICU support, one of whom led to maternal death 1/23 (4.3 %). 11/23 (48 %) of the patients had pre-existing co-morbidities, with morbid obesity 5/23 (21.7 %) and diabetes 4/23 (17.4 %) being the more commonly represented. Of the 23 pregnant patients 19 were in their third trimester of pregnancy and delivered; 7/19 (36.8 %) had preterm birth, 3/19 (15.8 %) developed adult respiratory distress syndrome before delivery, and 2/19 (10.5 %) had pre-eclampsia. 16/19 (84 %) of patients delivered by C-section. Out of the 20 new-borns, 18 were singletons with a set of twin. CONCLUSION: COVID-19 is associated with high prevalence of preterm birth, preeclampsia, and caesarean section compared to non-COVID pregnancies. COVID-19 infection was not found in the newborns and none developed severe neonatal complications.
  • |*Betacoronavirus[MESH]
  • |Adult[MESH]
  • |COVID-19[MESH]
  • |Cesarean Section/statistics & numerical data[MESH]
  • |Coronavirus Infections/*complications/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant, Newborn[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/virology[MESH]
  • |Pre-Eclampsia/epidemiology/virology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*virology[MESH]
  • |Pregnancy Outcome/*epidemiology[MESH]
  • |Premature Birth/epidemiology/virology[MESH]
  • |Prospective Studies[MESH]


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