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10.1016/j.amjcard.2020.06.063

http://scihub22266oqcxt.onion/10.1016/j.amjcard.2020.06.063
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suck abstract from ncbi


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pmid32732010      Am+J+Cardiol 2020 ; 131 (ä): 1-6
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  • Characteristics and Outcomes in Patients Presenting With COVID-19 and ST-Segment Elevation Myocardial Infarction #MMPMID32732010
  • Hamadeh A; Aldujeli A; Briedis K; Tecson KM; Sanz-Sanchez J; Al Dujeili M; Al-Obeidi A; Diez JL; Zaliunas R; Stoler RC; McCullough PA
  • Am J Cardiol 2020[Sep]; 131 (ä): 1-6 PMID32732010show ga
  • There is limited information regarding clinical characteristics and outcomes of patients with SARS-CoV-2 (COVID-19) disease presenting with ST-segment elevation myocardial infarction (STEMI). In this multicenter retrospective study, we reviewed charts of patients admitted with symptomatic COVID-19 infection and STEMI to a total of 4 hospitals spanning Italy, Lithuania, Spain and Iraq from February 1, 2020 to April 15, 2020. A total of 78 patients were included in this study, 49 (63%) of whom were men, with a median age of 65 [58, 71] years, and high comorbidity burden. During hospitalization, 8 (10%) developed acute respiratory distress syndrome, and 14 (18%) required mechanical ventilation. 19 (24%) patients were treated with primary Percutaneous Coronary Intervention (PCI) and 59 (76%) were treated with fibrinolytic therapy. 13 (17%) patients required cardiac resuscitation, and 9 (11%) died. For the 19 patients treated with primary PCI, 8 (42%) required intubation and 8 (42%) required cardiac resuscitation; stent thrombosis occurred in 4 patients (21%). A total of 5 patients (26%) died during hospitalization. 50 (85%) of the 59 patients initially treated with fibrinolytic therapy had successful fibrinolysis. The median time to reperfusion was 27 minutes [20, 34]. Hemorrhagic stroke occurred in 5 patients (9%). Six patients (10%) required invasive mechanical ventilation; 5 (9%) required cardiac resuscitation, and 4 (7%) died. In conclusion, this is the largest case series to-date of COVID-19 positive patients presenting with STEMI and spans 4 countries. We found a high rate of stent thrombosis, indicating a possible need to adapt STEMI management for COVID-19 patients.
  • |*Betacoronavirus[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Coronary Angiography[MESH]
  • |Coronavirus Infections/*complications/epidemiology[MESH]
  • |Female[MESH]
  • |Fibrinolytic Agents/*therapeutic use[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Italy/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Percutaneous Coronary Intervention/*methods[MESH]
  • |Pneumonia, Viral/*complications/epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |ST Elevation Myocardial Infarction/complications/diagnosis/*therapy[MESH]
  • |Spain/epidemiology[MESH]
  • |Survival Rate/trends[MESH]
  • |Thrombolytic Therapy/*methods[MESH]


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