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10.1016/j.ejogrb.2020.07.035

http://scihub22266oqcxt.onion/10.1016/j.ejogrb.2020.07.035
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32731057!7373691!32731057
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suck abstract from ncbi


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pmid32731057      Eur+J+Obstet+Gynecol+Reprod+Biol 2020 ; 252 (ä): 444-446
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  • Universal screening for SARS-CoV-2 in pregnant women at term admitted to an East London maternity unit #MMPMID32731057
  • Abeysuriya S; Wasif S; Counihan C; Shah N; Iliodromiti S; Cutino-Moguel MT; Saeed F; Velauthar L
  • Eur J Obstet Gynecol Reprod Biol 2020[Sep]; 252 (ä): 444-446 PMID32731057show ga
  • OBJECTIVE: To explore the prevalence of asymptomatic SARS-CoV-2 in the maternity population. STUDY DESIGN: Newham University Hospital based in East London serving a population with the highest death rate secondary to SARS-CoV-2 in the UK, commenced universal screening of all admissions to the Maternity Unit from 22nd April to 5th May, 2020. A proforma was created to capture key patient demographics, indication for admission and presence of SARS-CoV-2 related symptoms at the point of presentation. RESULTS: A total of 180 women with a mean age of 29.9 (SD 7.4) years, at a median gestation of 39 (IQR 37?+?1-40?+?3) weeks underwent universal screening with nasopharyngeal PCR swabs during the two-week period of the study. BAME identity or parity was not associated with the likelihood of a positive result. Seven women (3.9 %, 1.6-7.8) were tested positive for SARS-CoV-2, of whom 6 (3.3 %, 1.2-7.1) were asymptomatic; 85.7 % (42.1-99.6) of the SARS-CoV-2 positive women were asymptomatic. The sensitivity of symptom-driven testing was 14.3 % (0.36-57.87) and specificity was 91.86 % (86.72-95.48) with a positive predictive value of 6.67 % (1.08-31.95) and a negative predictive value of 96.34 % (95.10-97.28). CONCLUSION: The prevalence of SARS-CoV-2 in the maternity population served by Newham University Hospital was 3.9 %, four weeks after lockdown. Of the women who were found to be SARS-CoV-2 positive, a high proportion (87.9 %) were asymptomatic. These findings support the need for universal testing to enable targeted isolation and robust infectious control measures to mitigate outbreaks of SARS-CoV-2 in maternity units.
  • |*Betacoronavirus[MESH]
  • |*Clinical Laboratory Techniques[MESH]
  • |Adult[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Coronavirus Infections/*diagnosis/epidemiology/virology[MESH]
  • |Delivery Rooms[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |London/epidemiology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/epidemiology/virology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*diagnosis/epidemiology/virology[MESH]
  • |Prenatal Diagnosis/*methods[MESH]
  • |Prevalence[MESH]
  • |SARS-CoV-2[MESH]


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