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10.1016/j.bios.2020.112361

http://scihub22266oqcxt.onion/10.1016/j.bios.2020.112361
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32729494!7834411!32729494
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suck abstract from ncbi


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pmid32729494      Biosens+Bioelectron 2020 ; 165 (ä): 112361
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  • Clinically practiced and commercially viable nanobio engineered analytical methods for COVID-19 diagnosis #MMPMID32729494
  • Mahapatra S; Chandra P
  • Biosens Bioelectron 2020[Oct]; 165 (ä): 112361 PMID32729494show ga
  • The recent outbreak of the coronavirus disease (COVID-19) has left the world clueless. As the WHO declares this new contagion as a pandemic on the 11(th) of March 2020, the alarming rate of the spawn of the disease in such a short period has disarranged the globe. Standing against this situation researchers are strenuously searching for the key traits responsible for this pandemic. As knowledge regarding the dynamics and host-path interaction of COVID-19 causing Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is currently unknown, the formulation of strategies concerning antiviral treatment, vaccination, and epidemiological control stands crucial. Before designing adequate therapeutic strategies, it is extremely essential to diagnose the disease at the outset as early detection can have a greater impact on building health system capacity. Hence, a comprehensive review of strategies for COVID-19 diagnosis is essential in this existing global situation. In this review, sequentially, we have provided the clinical details along with genetic and proteomic biomarkers related to COVID-19. The article systematically enlightens a clear overview of the clinically adopted techniques for the detection of COVID-19 including oligonucleotide-based molecular detection, Point-of-Care immunodiagnostics, radiographical analysis/sensing system, and newly developed biosensing prototypes having commercial viability. The commercial kits/analytical methods based-sensing strategies have also been tabulated categorically. The critical insights on the developer, commercial brand name, detection methods, technical operational details, detection time, clinical specimen, status, the limit of detection/detection ability have been discussed comprehensively. We believe that this review may provide scientists, clinicians and healthcare manufacturers valuable information regarding the most recent developments/approaches towards COVID-19 diagnosis.
  • |*Lab-On-A-Chip Devices[MESH]
  • |*Point-of-Care Testing[MESH]
  • |Animals[MESH]
  • |Antibodies, Immobilized/chemistry[MESH]
  • |Betacoronavirus/genetics/*isolation & purification[MESH]
  • |Biomarkers/analysis[MESH]
  • |Biosensing Techniques/instrumentation/*methods[MESH]
  • |COVID-19[MESH]
  • |Clustered Regularly Interspaced Short Palindromic Repeats[MESH]
  • |Coronavirus Infections/blood/*diagnosis/virology[MESH]
  • |Equipment Design[MESH]
  • |Humans[MESH]
  • |Immunoassay/instrumentation/methods[MESH]
  • |Nanostructures/chemistry[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/blood/*diagnosis/virology[MESH]
  • |Radiographic Image Enhancement/instrumentation/methods[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction/instrumentation/methods[MESH]


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