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10.1080/17512433.2020.1803740 http://scihub22266oqcxt.onion/10.1080/17512433.2020.1803740 32729363!ä!32729363 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Clin+Pharmacol 2020 ; 13 (9): 945-956 Nephropedia Template TP {{tp|p=32729363|t=2020. Development and progress of clinical trials of Coronavirus Disease 2019 antiviral drugs |pdf=|usr=}}{{32729363}} gab.com Text Development and progress of clinical trials of Coronavirus Disease 2019 antiviral drugs JO: Expert Rev Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=32729363 #FOAvip INTRODUCTION: We have summarized and analyzed the clinical trial registration status and the latest research progress of eight major antiviral drugs during the epidemic of Coronavirus Disease 2019 (COVID-19), which can provide reference methods for clinical formulation of the best antiviral treatment. AREAS COVERED: We used the generic names of 8 antiviral drugs as keywords to search and analyze the COVID-19-related clinical trials registered in Chinese Clinical Trial Registry and ClinicalTrials.gov. Then, we used the keywords to obtain and summarize their clinical research results related to COVID-19 in CNKI, WANFANG, CQVIP, and PubMed database. EXPERT OPINION: The registration system of clinical trials and the level of clinical trial design need to be further improved. At present, no specific drug has been found for the treatment of COVID-19, the efficacy of antiviral drugs mostly comes from small sample studies or retrospective studies, and the level of clinical evidence is low. Besides, multi-drug combination therapy may become a more effective treatment choice, but the drug interactions and adverse drug reactions also need to be closely monitored. In summary, the safety and efficacy of various antiviral drugs need to be confirmed by large samples and high-quality RCT studies. Twit Text FOAVip Development and progress of clinical trials of Coronavirus Disease 2019 antiviral drugs ????Expert Rev Clin Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=32729363 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32729363 #FOAvip English Wikipedia <ref>{{Cite pmid|32729363}}</ref> Development and progress of clinical trials of Coronavirus Disease 2019 antiviral drugs #MMPMID32729363 Pang W; Wang Q; Zhao Z Expert Rev Clin Pharmacol 2020[Sep]; 13 (9): 945-956 PMID32729363show ga INTRODUCTION: We have summarized and analyzed the clinical trial registration status and the latest research progress of eight major antiviral drugs during the epidemic of Coronavirus Disease 2019 (COVID-19), which can provide reference methods for clinical formulation of the best antiviral treatment. AREAS COVERED: We used the generic names of 8 antiviral drugs as keywords to search and analyze the COVID-19-related clinical trials registered in Chinese Clinical Trial Registry and ClinicalTrials.gov. Then, we used the keywords to obtain and summarize their clinical research results related to COVID-19 in CNKI, WANFANG, CQVIP, and PubMed database. EXPERT OPINION: The registration system of clinical trials and the level of clinical trial design need to be further improved. At present, no specific drug has been found for the treatment of COVID-19, the efficacy of antiviral drugs mostly comes from small sample studies or retrospective studies, and the level of clinical evidence is low. Besides, multi-drug combination therapy may become a more effective treatment choice, but the drug interactions and adverse drug reactions also need to be closely monitored. In summary, the safety and efficacy of various antiviral drugs need to be confirmed by large samples and high-quality RCT studies. |*Betacoronavirus/drug effects[MESH] |*Drug Development[MESH] |*Research Design[MESH] |Antiviral Agents/adverse effects/pharmacology/*therapeutic use[MESH] |COVID-19[MESH] |Clinical Trials as Topic[MESH] |Coronavirus Infections/*drug therapy[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH]Development and progress of clinical trials of Coronavirus Disease 201(epmc).pdf DeepDyve Pubget Overpricing