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10.1159/000510179

http://scihub22266oqcxt.onion/10.1159/000510179
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32726783!7490485!32726783
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suck abstract from ncbi


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pmid32726783      Acta+Haematol 2021 ; 144 (3): 314-318
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  • JAK/STAT Pathway Inhibition May Be a Promising Therapy for COVID-19-Related Hyperinflammation in Hematologic Patients #MMPMID32726783
  • Rojas P; Sarmiento M
  • Acta Haematol 2021[]; 144 (3): 314-318 PMID32726783show ga
  • COVID-19 has rapidly become a major concern for the health systems worldwide. Its high contagiousness and associated mortality demand the discovery of helpful interventions with promising safety profile. Here, we report 3 severe COVID-19 cases, which achieved rapid and sustained improvement in outcome with the use of ruxolitinib, a JAK/STAT pathway inhibitor.
  • |Adult[MESH]
  • |C-Reactive Protein/analysis[MESH]
  • |COVID-19/complications/*pathology/virology[MESH]
  • |Ferritins/analysis[MESH]
  • |Fibrin Fibrinogen Degradation Products/analysis[MESH]
  • |Hematologic Diseases/*drug therapy/etiology[MESH]
  • |Humans[MESH]
  • |Janus Kinase Inhibitors/pharmacology/*therapeutic use[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nitriles[MESH]
  • |Pyrazoles/pharmacology/therapeutic use[MESH]
  • |Pyrimidines[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]
  • |Signal Transduction/drug effects[MESH]
  • |Thorax/diagnostic imaging[MESH]


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