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10.1093/infdis/jiaa471

http://scihub22266oqcxt.onion/10.1093/infdis/jiaa471
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32726430!7454736!32726430
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suck abstract from ncbi


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pmid32726430      J+Infect+Dis 2020 ; 222 (8): 1289-1292
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  • Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2 #MMPMID32726430
  • Meister TL; Bruggemann Y; Todt D; Conzelmann C; Muller JA; Gross R; Munch J; Krawczyk A; Steinmann J; Steinmann J; Pfaender S; Steinmann E
  • J Infect Dis 2020[Sep]; 222 (8): 1289-1292 PMID32726430show ga
  • The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during early coronavirus disease 2019, thus advocating application of oral antiseptics. However, the antiviral efficacy of oral rinsing solutions against SARS-CoV-2 has not been examined. Here, we evaluated the virucidal activity of different available oral rinses against SARS-CoV-2 under conditions mimicking nasopharyngeal secretions. Several formulations with significant SARS-CoV-2 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of saliva and could thus lower the transmission of SARS-CoV-2.
  • |Animals[MESH]
  • |Antiviral Agents/*pharmacology[MESH]
  • |Betacoronavirus/*drug effects/physiology[MESH]
  • |COVID-19[MESH]
  • |Chlorocebus aethiops[MESH]
  • |Coronavirus Infections/*drug therapy/transmission/*virology[MESH]
  • |Humans[MESH]
  • |Mouthwashes/*pharmacology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy/transmission/*virology[MESH]
  • |SARS-CoV-2[MESH]
  • |Saliva/virology[MESH]
  • |Vero Cells[MESH]
  • |Viral Load/drug effects[MESH]


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