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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 West+J+Emerg+Med 2020 ; 21 (4): 760-763 Nephropedia Template TP
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Brief Review of Chloroquine and Hydroxychloroquine Toxicity and Management #MMPMID32726238
Lebin JA; LeSaint KT
West J Emerg Med 2020[Jun]; 21 (4): 760-763 PMID32726238show ga
As of April 21, 2020, more than 2.5 million cases of coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, have been reported in 210 countries and territories, with the death toll at 171,810. Both chloroquine and hydroxychloroquine have gained considerable media attention as possible therapies, resulting in a significant surge in demand. In overdose, both medications can cause severe, potentially life-threatening effects. Here, we present a brief overview of the pharmacology of chloroquine and hydroxychloroquine, manifestations of toxicity, and treatment considerations.