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10.1007/s15010-020-01473-w

http://scihub22266oqcxt.onion/10.1007/s15010-020-01473-w
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suck abstract from ncbi


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pmid32725595      Infection 2020 ; 48 (6): 861-870
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  • Cardiac manifestations of COVID-19 in Shenzhen, China #MMPMID32725595
  • Zeng JH; Wu WB; Qu JX; Wang Y; Dong CF; Luo YF; Zhou D; Feng WX; Feng C
  • Infection 2020[Dec]; 48 (6): 861-870 PMID32725595show ga
  • PURPOSE: The coronavirus disease 2019 (COVID-19) outbreak has become a global public health concern; however, relatively few detailed reports of related cardiac injury are available. The aims of this study were to compare the clinical and echocardiographic characteristics of inpatients in the intensive-care unit (ICU) and non-ICU patients. METHODS: We recruited 416 patients diagnosed with COVID-19 and divided them into two groups: ICU (n = 35) and non-ICU (n = 381). Medical histories, laboratory findings, and echocardiography data were compared. RESULTS: The levels of myocardial injury markers in ICU vs non-ICU patients were as follows: troponin I (0.029 ng/mL [0.007-0.063] vs 0.006 ng/mL [0.006-0.006]) and myoglobin (65.45 mug/L [39.77-130.57] vs 37.00 mug/L [26.40-53.54]). Echocardiographic findings included ventricular wall thickening (12 [39%] vs 1 [4%]), pulmonary hypertension (9 [29%] vs 0 [0%]), and reduced left-ventricular ejection fraction (5 [16%] vs 0 [0%]). Overall, 10% of the ICU patients presented with right heart enlargement, thickened right-ventricular wall, decreased right heart function, and pericardial effusion. Cardiac complications were more common in ICU patients, including acute cardiac injury (21 [60%] vs 13 [3%]) (including 2 cases of fulminant myocarditis), atrial or ventricular tachyarrhythmia (3 [9%] vs 3 [1%]), and acute heart failure (5 [14%] vs 0 [0%]). CONCLUSION: Myocardial injury marker elevation, ventricular wall thickening, pulmonary artery hypertension, and cardiac complications including acute myocardial injury, arrhythmia, and acute heart failure are more common in ICU patients with COVID-19. Cardiac injury in COVID-19 patients may be related more to the systemic response after infection rather than direct damage by coronavirus.
  • |*SARS-CoV-2[MESH]
  • |Aged[MESH]
  • |COVID-19/*complications/diagnosis/*epidemiology/virology[MESH]
  • |China/epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Critical Care[MESH]
  • |Echocardiography[MESH]
  • |Female[MESH]
  • |Heart Diseases/diagnosis/*epidemiology/*etiology/mortality[MESH]
  • |Heart Function Tests[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Myocarditis/diagnosis/epidemiology/etiology[MESH]
  • |Prognosis[MESH]
  • |Radiography, Thoracic[MESH]


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