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10.3390/v12080798 http://scihub22266oqcxt.onion/10.3390/v12080798 32722343!7472216!32722343     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2020 ; 12 (8): ä Nephropedia Template TP {{tp|p=32722343|t=2020. Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic |pdf=|usr=}}{{32722343}} gab.com Text Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32722343 #FOAvip The aim of this study is the characterization and genomic tracing by phylogenetic analyses of 59 new SARS-CoV-2 Italian isolates obtained from patients attending clinical centres in North and Central Italy until the end of April 2020. All but one of the newly-characterized genomes belonged to the lineage B.1, the most frequently identified in European countries, including Italy. Only a single sequence was found to belong to lineage B. A mean of 6 nucleotide substitutions per viral genome was observed, without significant differences between synonymous and non-synonymous mutations, indicating genetic drift as a major source for virus evolution. tMRCA estimation confirmed the probable origin of the epidemic between the end of January and the beginning of February with a rapid increase in the number of infections between the end of February and mid-March. Since early February, an effective reproduction number (R(e)) greater than 1 was estimated, which then increased reaching the peak of 2.3 in early March, confirming the circulation of the virus before the first COVID-19 cases were documented. Continuous use of state-of-the-art methods for molecular surveillance is warranted to trace virus circulation and evolution and inform effective prevention and containment of future SARS-CoV-2 outbreaks. Twit Text FOAVip Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32722343 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32722343 #FOAvip English Wikipedia <ref>{{Cite pmid|32722343}}</ref> Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic #MMPMID32722343 Lai A; Bergna A; Caucci S; Clementi N; Vicenti I; Dragoni F; Cattelan AM; Menzo S; Pan A; Callegaro A; Tagliabracci A; Caruso A; Caccuri F; Ronchiadin S; Balotta C; Zazzi M; Vaccher E; Clementi M; Galli M; Zehender G Viruses 2020[Jul]; 12 (8): ä PMID32722343show ga The aim of this study is the characterization and genomic tracing by phylogenetic analyses of 59 new SARS-CoV-2 Italian isolates obtained from patients attending clinical centres in North and Central Italy until the end of April 2020. All but one of the newly-characterized genomes belonged to the lineage B.1, the most frequently identified in European countries, including Italy. Only a single sequence was found to belong to lineage B. A mean of 6 nucleotide substitutions per viral genome was observed, without significant differences between synonymous and non-synonymous mutations, indicating genetic drift as a major source for virus evolution. tMRCA estimation confirmed the probable origin of the epidemic between the end of January and the beginning of February with a rapid increase in the number of infections between the end of February and mid-March. Since early February, an effective reproduction number (R(e)) greater than 1 was estimated, which then increased reaching the peak of 2.3 in early March, confirming the circulation of the virus before the first COVID-19 cases were documented. Continuous use of state-of-the-art methods for molecular surveillance is warranted to trace virus circulation and evolution and inform effective prevention and containment of future SARS-CoV-2 outbreaks. |*Pandemics[MESH] |Bayes Theorem[MESH] |Betacoronavirus/*classification/*genetics/isolation & purification[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology/*virology[MESH] |Epidemiological Monitoring[MESH] |Genome, Viral[MESH] |Humans[MESH] |Italy/epidemiology[MESH] |Likelihood Functions[MESH] |Molecular Epidemiology[MESH] |Molecular Typing[MESH] |Mutation[MESH] |Phylogeny[MESH] |Pneumonia, Viral/*epidemiology/*virology[MESH] |SARS-CoV-2[MESH] |Time Factors[MESH]Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of (epmc).pdf DeepDyve Pubget Overpricing