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10.1016/j.ijid.2020.07.025

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.07.025
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32721534!7834290!32721534
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suck abstract from ncbi


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pmid32721534      Int+J+Infect+Dis 2020 ; 99 (ä): 1-2
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  • Adsorptive granulocyte and monocyte apheresis: A potentially relevant therapeutic option for COVID-19 #MMPMID32721534
  • Kanekura T; Kawahara K
  • Int J Infect Dis 2020[Oct]; 99 (ä): 1-2 PMID32721534show ga
  • The overproduction of proinflammatory cytokines and subsequent thromboembolism are major problems of coronavirus disease 2019 (COVID-19). Adsorptive granulocyte and monocyte apheresis (GMA), used for ulcerative colitis, is an extracorporeal therapy designed to remove activated myeloid lineage cells. Previous studies have demonstrated that GMA decreases proinflammatory cytokines and neutrophil-platelet aggregates. The effect of GMA on COVID-19 in a patient with ulcerative colitis was recently reported. The modes of action of GMA together with the findings of this case report indicate that GMA could be a relevant treatment option for COVID-19.
  • |*Betacoronavirus[MESH]
  • |*Granulocytes[MESH]
  • |*Monocytes[MESH]
  • |Adsorption[MESH]
  • |Adult[MESH]
  • |Blood Component Removal/*methods[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*therapy[MESH]
  • |Cytokines/metabolism[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Neutrophils[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*therapy[MESH]
  • |SARS-CoV-2[MESH]


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