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10.1016/j.bjid.2020.06.009

http://scihub22266oqcxt.onion/10.1016/j.bjid.2020.06.009
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32721387!7381934!32721387
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suck abstract from ncbi


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pmid32721387      Braz+J+Infect+Dis 2020 ; 24 (4): 343-348
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  • A predictive score for COVID-19 diagnosis using clinical, laboratory and chest image data #MMPMID32721387
  • Vieceli T; Oliveira Filho CM; Berger M; Saadi MP; Salvador PA; Anizelli LB; Crivelaro PCF; Butzke M; Zappelini RS; Seligman BGDS; Seligman R
  • Braz J Infect Dis 2020[Jul]; 24 (4): 343-348 PMID32721387show ga
  • OBJECTIVES: Differential diagnosis of COVID-19 includes a broad range of conditions. Prioritizing containment efforts, protective personal equipment and testing can be challenging. Our aim was to develop a tool to identify patients with higher probability of COVID-19 diagnosis at admission. METHODS: This cross-sectional study analyzed data from 100 patients admitted with suspected COVID-19. Predictive models of COVID-19 diagnosis were performed based on radiology, clinical and laboratory findings; bootstrapping was performed in order to account for overfitting. RESULTS: A total of 29% of patients tested positive for SARS-CoV-2. Variables associated with COVID-19 diagnosis in multivariate analysis were leukocyte count 273U/L, and chest radiographic abnormality. A predictive score was built for COVID-19 diagnosis, with an area under ROC curve of 0.847 (95% CI 0.77-0.92), 96% sensitivity and 73.5% specificity. After bootstrapping, the corrected AUC for this model was 0.827 (95% CI 0.75-0.90). CONCLUSIONS: Considering unavailability of RT-PCR at some centers, as well as its questionable early sensitivity, other tools might be used in order to identify patients who should be prioritized for testing, re-testing and admission to isolated wards. We propose a predictive score that can be easily applied in clinical practice. This score is yet to be validated in larger populations.
  • |*Clinical Laboratory Techniques[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Coronavirus Infections/*diagnosis[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis[MESH]
  • |Predictive Value of Tests[MESH]
  • |Radiography, Thoracic[MESH]
  • |SARS-CoV-2[MESH]


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