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10.3389/fvets.2020.00457 http://scihub22266oqcxt.onion/10.3389/fvets.2020.00457 32719819!7349190!32719819     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Vet+Sci 2020 ; 7 (ä): 457 Nephropedia Template TP {{tp|p=32719819|t=2020. Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species |pdf=|usr=}}{{32719819}} gab.com Text Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species JO: Front Vet Sci http://www.kidney.de/pget.php?&tw=1&pmid=32719819 #FOAvip Human beings are currently experiencing a serious public health event. Novel coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), has infected about 3 million people worldwide and killed more than 200,000, most being the elderly or people with potential chronic diseases or in immunosuppressive states. According to big data analysis, there are many proteins homologous to or interacting with the angiotensin-converting enzyme 2 (ACE2), which, therefore, may not be the only receptor for the novel coronavirus; other receptors may also exist in host cells of different species. These potential receptors may also play an important role in the infection process of the novel coronavirus. The current study aimed to discover such key proteins or receptors and analyze the susceptibility of different animals to the novel coronavirus, in order to reveal the transmission process of the virus in cross-species infection. We analyzed the proteins coded by the ACE2 gene in different mammalian species and predicted their correlation and homology with the human ACE2 receptor. The major finding of our predictive analysis suggested ACE2 gene-encoded proteins to be highly homologous across mammals. Based on their high homology, their possibility of binding the spike-protein of SARS-CoV-2 is quite high and species such as Felis catus, Bos taurus, Rattus norvegicus etc. may be potential susceptible hosts; special monitoring is particularly required for livestock that are in close contact with humans. Our results might provide ideas for the prevention and control of the novel coronavirus pneumonia. Twit Text FOAVip Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species ????Front Vet Sci http://www.kidney.de/pget.php?&tw=1&pmid=32719819 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32719819 #FOAvip English Wikipedia <ref>{{Cite pmid|32719819}}</ref> Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species #MMPMID32719819 Cao Y; Sun Y; Tian X; Bai Z; Gong Y; Qi J; Liu D; Liu W; Li J Front Vet Sci 2020[]; 7 (ä): 457 PMID32719819show ga Human beings are currently experiencing a serious public health event. Novel coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), has infected about 3 million people worldwide and killed more than 200,000, most being the elderly or people with potential chronic diseases or in immunosuppressive states. According to big data analysis, there are many proteins homologous to or interacting with the angiotensin-converting enzyme 2 (ACE2), which, therefore, may not be the only receptor for the novel coronavirus; other receptors may also exist in host cells of different species. These potential receptors may also play an important role in the infection process of the novel coronavirus. The current study aimed to discover such key proteins or receptors and analyze the susceptibility of different animals to the novel coronavirus, in order to reveal the transmission process of the virus in cross-species infection. We analyzed the proteins coded by the ACE2 gene in different mammalian species and predicted their correlation and homology with the human ACE2 receptor. The major finding of our predictive analysis suggested ACE2 gene-encoded proteins to be highly homologous across mammals. Based on their high homology, their possibility of binding the spike-protein of SARS-CoV-2 is quite high and species such as Felis catus, Bos taurus, Rattus norvegicus etc. may be potential susceptible hosts; special monitoring is particularly required for livestock that are in close contact with humans. Our results might provide ideas for the prevention and control of the novel coronavirus pneumonia. äAnalysis of ACE2 Gene-Encoded Proteins Across Mammalian Species (epmc).pdf DeepDyve Pubget Overpricing