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10.3389/fmicb.2020.01576

http://scihub22266oqcxt.onion/10.3389/fmicb.2020.01576
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32719672!7347906!32719672
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suck abstract from ncbi


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pmid32719672      Front+Microbiol 2020 ; 11 (ä): 1576
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  • Severe Acute Respiratory Syndrome Coronavirus 2: From Gene Structure to Pathogenic Mechanisms and Potential Therapy #MMPMID32719672
  • Wu J; Yuan X; Wang B; Gu R; Li W; Xiang X; Tang L; Sun H
  • Front Microbiol 2020[]; 11 (ä): 1576 PMID32719672show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly emerging respiratory virus with high morbidity, which was named coronavirus disease 2019 (COVID-19) by World Health Organization (WHO). COVID-19 has triggered a series of threats to global public health. Even worse, new cases of COVID-19 infection are still increasing rapidly. Therefore, it is imperative that various effective vaccines and drugs should be developed to prevent and treat COVID-19 and reduce the serious impact on human beings. For this purpose, detailed information about the pathogenesis of COVID-19 at the cellular and molecular levels is urgently needed. In this review, we summarized the current understanding on gene structure, protein function, and pathogenic mechanisms of SARS-CoV-2. Based on the above, we refined the correlations among gene structure, protein function, and pathogenic mechanisms of SARS-CoV-2. Importantly, we further discussed potential therapeutic targets, aiming to accelerate the advanced design and development of vaccines and therapeutic drugs against COVID-19.
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