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10.1016/j.cytogfr.2020.07.005 http://scihub22266oqcxt.onion/10.1016/j.cytogfr.2020.07.005 32718830!7333629!32718830     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cytokine+Growth+Factor+Rev 2020 ; 56 (ä): 39-48 Nephropedia Template TP {{tp|p=32718830|t=2020. Engineering and combining oncolytic measles virus for cancer therapy |pdf=|usr=}}{{32718830}} gab.com Text Engineering and combining oncolytic measles virus for cancer therapy JO: Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=32718830 #FOAvip Cancer immunotherapy using tumor-selective, oncolytic viruses is an emerging therapeutic option for solid and hematologic malignancies. A considerable variety of viruses ranging from small picornaviruses to large poxviruses are currently being investigated as potential candidates. In the early days of virotherapy, non-engineered wild-type or vaccine-strain viruses were employed. However, these viruses often did not fully satisfy the major criteria of safety and efficacy. Since the advent of reverse genetics systems for manipulating various classes of viruses, the field has shifted to developing genetically engineered viruses with an improved therapeutic index. In this review, we will summarize the concepts and strategies of multi-level genetic engineering of oncolytic measles virus, a prime candidate for cancer immunovirotherapy. Furthermore, we will provide a brief overview of measles virus-based multimodal combination therapies for improved tumor control and clinical efficacy. Twit Text FOAVip Engineering and combining oncolytic measles virus for cancer therapy ????Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=32718830 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32718830 #FOAvip English Wikipedia <ref>{{Cite pmid|32718830}}</ref> Engineering and combining oncolytic measles virus for cancer therapy #MMPMID32718830 Leber MF; Neault S; Jirovec E; Barkley R; Said A; Bell JC; Ungerechts G Cytokine Growth Factor Rev 2020[Dec]; 56 (ä): 39-48 PMID32718830show ga Cancer immunotherapy using tumor-selective, oncolytic viruses is an emerging therapeutic option for solid and hematologic malignancies. A considerable variety of viruses ranging from small picornaviruses to large poxviruses are currently being investigated as potential candidates. In the early days of virotherapy, non-engineered wild-type or vaccine-strain viruses were employed. However, these viruses often did not fully satisfy the major criteria of safety and efficacy. Since the advent of reverse genetics systems for manipulating various classes of viruses, the field has shifted to developing genetically engineered viruses with an improved therapeutic index. In this review, we will summarize the concepts and strategies of multi-level genetic engineering of oncolytic measles virus, a prime candidate for cancer immunovirotherapy. Furthermore, we will provide a brief overview of measles virus-based multimodal combination therapies for improved tumor control and clinical efficacy. |*Neoplasms/therapy[MESH] |*Oncolytic Virotherapy[MESH] |*Oncolytic Viruses[MESH] |Humans[MESH] |Immunotherapy[MESH]Engineering and combining oncolytic measles virus for cancer therapy (epmc).pdf DeepDyve Pubget Overpricing