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10.1016/j.cmi.2020.07.030

http://scihub22266oqcxt.onion/10.1016/j.cmi.2020.07.030
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32717417!7378475!32717417
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suck abstract from ncbi


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pmid32717417      Clin+Microbiol+Infect 2020 ; 26 (10): 1417.e5-1417.e8
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  • CT lung lesions as predictors of early death or ICU admission in COVID-19 patients #MMPMID32717417
  • Ruch Y; Kaeuffer C; Ohana M; Labani A; Fabacher T; Bilbault P; Kepka S; Solis M; Greigert V; Lefebvre N; Hansmann Y; Danion F
  • Clin Microbiol Infect 2020[Oct]; 26 (10): 1417.e5-1417.e8 PMID32717417show ga
  • OBJECTIVE: The main objective of this study was to investigate the prognostic value of early systematic chest computed tomography (CT) with quantification of lung lesions in coronavirus disease 2019 (COVID-19) patients. METHODS: We studied 572 patients diagnosed with COVID-19 (confirmed using polymerase chain reaction) for whom a chest CT was performed at hospital admission. Visual quantification was used to classify patients as per the percentage of lung parenchyma affected by COVID-19 lesions: normal CT, 0-10%, 11-25%, 26-50%, 51-75% and >75%. The primary endpoint was severe disease, defined by death or admission to the intensive care unit in the 7 days following first admission. RESULTS: The mean patient age was 66.0 +/- 16.0 years, and 343/572 (60.0%) were men. The primary endpoint occurred in 206/572 patients (36.0%). The extent of lesions on initial CT was independently associated with prognosis (odds ratio = 2.35, 95% confidence interval 1.24-4.46; p < 0.01). Most patients with lung involvement >50% (66/95, 69.5%) developed severe disease compared to patients with lung involvement of 26-50% (70/171, 40.9%) and
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus/genetics/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Coronavirus Infections/diagnosis/*diagnostic imaging/*mortality/physiopathology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Lung/*diagnostic imaging/physiopathology/virology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnostic imaging/*mortality/physiopathology/virology[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Survival Analysis[MESH]


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