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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Matern+Fetal+Neonatal+Med 2022 ; 35 (16): 3040-3043 Nephropedia Template TP
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ADRS due to COVID-19 in midterm pregnancy: successful management with plasma transfusion and corticosteroids #MMPMID32715804
Soleimani Z; Soleimani A
J Matern Fetal Neonatal Med 2022[Aug]; 35 (16): 3040-3043 PMID32715804show ga
BACKGROUND: Management of acute respiratory distress syndrome (ARDS) in pregnant women infected with new severe acute respiratory syndrome Corona virus 2 (SARS-CoV(2)) is a challenging clinical task. CASE: A 30- year-old woman (gravid 3, parity 2) presented at her 21 and 2/7 weeks gestation (pre pregnancy BMI: 36.1 kg/m(2)), with ARDS caused by SARS-CoV(2) infection. She received lopinavir/ritonavir and azithromycin as well as early methyl prednisolone therapy. Given the persistent hypoxemia despite oxygen therapy via non rebreather face mask (FiO(2):80%), convalescent plasma transfusion was administered that led to a mild clinical improvement as well as decrease in inflammatory markers. Growth of her fetus assessed by obstetric sonography was normal during hospital stay. CONCLUSION: Judicious corticosteroid therapy along with convalescent plasma transfusion to suppress viremia and cytokine storm can lead to favorable outcome in the pregnant women with ARDS caused by SARS-CoV(2) infection without superimposed bacterial infection.