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10.1007/s13730-020-00512-7

http://scihub22266oqcxt.onion/10.1007/s13730-020-00512-7
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32715376!7382919!32715376
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suck abstract from ncbi


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pmid32715376      CEN+Case+Rep 2021 ; 10 (1): 42-45
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  • Successful treatment of two Japanese ESRD cases with severe COVID-19 pneumonia #MMPMID32715376
  • Abe T; Izumo T; Ueda A; Hayashi M; Ishibashi Y
  • CEN Case Rep 2021[Feb]; 10 (1): 42-45 PMID32715376show ga
  • Novel coronavirus disease 2019 (COVID-19) is a highly infectious and deadly disease, spreading worldwide. There are limited data about the clinical course of end-stage renal disease (ESRD) patients infected with COVID-19. However, previous cohort studies showed a high mortality rate of ESRD patients infected with COVID-19. We report here two Japanese ESRD patients confirmed with severe COVID-19 pneumonia. Case 1 was a 60-year-old man with ESRD due to diabetic nephropathy who were infected with COVID-19 and exhibited acute respiratory distress syndrome (ARDS) requiring mechanical ventilation and intensive care unit (ICU) admission. He was treated with tocilizumab and intravenous immunoglobulin (IVIG). After 6 days of treatment in ICU, he was extubated. Case 2 was a 68-year-old woman undergoing maintenance hemodialysis for 17 years who also exhibited ARDS due to COVID-19. Her clinical course resembles case 1. Our experience of these two cases indicates that anti-cytokine therapy might be effective for severe COVID-19 pneumonia in ESRD patients.
  • |Aged[MESH]
  • |Antibodies, Monoclonal, Humanized/therapeutic use[MESH]
  • |Antiviral Agents/therapeutic use[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |COVID-19/*complications/*therapy[MESH]
  • |Critical Care[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunization, Passive[MESH]
  • |Immunoglobulins, Intravenous/therapeutic use[MESH]
  • |Japan[MESH]
  • |Kidney Failure, Chronic/*complications/therapy[MESH]
  • |Male[MESH]
  • |Renal Dialysis[MESH]
  • |Respiration, Artificial[MESH]


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