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10.1016/j.ijid.2020.07.020

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.07.020
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32712426!7378010!32712426
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suck abstract from ncbi


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pmid32712426      Int+J+Infect+Dis 2020 ; 98 (ä): 398-400
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  • Encephalopathy in severe SARS-CoV2 infection: Inflammatory or infectious? #MMPMID32712426
  • Abenza-Abildua MJ; Novo-Aparicio S; Moreno-Zabaleta R; Algarra-Lucas MC; Rojo Moreno-Arcones B; Salvador-Maya MA; Navacerrada-Barrero FJ; Ojeda-Ruiz de Luna J; Perez-Lopez C; Fraile-Vicente JM; Suarez-Garcia I; Suarez-Gisbert E; Palacios-Castano JA; Ramirez-Prieto MT
  • Int J Infect Dis 2020[Sep]; 98 (ä): 398-400 PMID32712426show ga
  • Concerning the letter by Moriguchi et al., we describe our experience with a case of encephalopathy with and atypical damage on magnetic resonance imaging (MRI) in a patient with severe infection due to the SARS-CoV2 virus. A 56-year-old woman, without previous pathologies, developed cough, fever, and respiratory failure for five days, after returning from a 6-day trip to Venice. Chest radiography shows a large bilateral interstitial infiltrate. In the first 24 hours, she was admitted to the Intensive Care Unit (ICU) for severe respiratory failure and positive protein chain reaction-PCR in nasal exudate. She needed intubation for ten days. In the first 48 hours outside the ICU, she developed an acute confusional syndrome (hyperactive delirium). Neurological examination showed temporal-spatial disorientation and incoherent fluent speech. An electroencephalogram (EEG) showed generalized hypovoltaic activity. Cranial magnetic resonance imaging showed a bilateral and symmetrical increase in the supratentorial white matter's signal intensity, with a discrete thickening of both temporal lobes, with a slight increase in signal intensity and a sequence of normal diffusion. The lumbar puncture showed no changes (glucose 71 mg/dL, protein 30 mg/dL, 1 leukocyte). Within 72 hours of starting symptoms, she was neurologically asymptomatic. Our final diagnosis was an inflammatory encephalopathy related to a SARS-CoV2 infection.
  • |Betacoronavirus/genetics/isolation & purification/*physiology[MESH]
  • |Brain Diseases/diagnostic imaging/*etiology/immunology/virology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications/immunology/virology[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Magnetic Resonance Imaging[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/immunology/virology[MESH]


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