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Children and COVID-19: Microbiological and immunological insights #MMPMID32710652
Buonsenso D; Sali M; Pata D; De Rose C; Sanguinetti M; Valentini P; Delogu G
Pediatr Pulmonol 2020[Oct]; 55 (10): 2547-2555 PMID32710652show ga
Since its first description in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide being declared a pandemic by the World Health Organization. More than 10.3 million people have been infected and more than 506 000 people died. However, SARS-CoV-2 had a lower impact on the pediatric population. Only about 1% to 2% of infected people are children and few deaths under the age of 14 are described so far. In this article, we discuss microbiological and immunological characteristics of SARS-CoV-2 infection in children highlighting the main differences from adult SARS-CoV-2 infection.