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10.1111/aji.13313 http://scihub22266oqcxt.onion/10.1111/aji.13313 32710571!ä!32710571 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Reprod+Immunol 2021 ; 85 (4): e13313 Nephropedia Template TP {{tp|p=32710571|t=2021. Clinical molecular genetics evaluation in women with reproductive failures |pdf=|usr=}}{{32710571}} gab.com Text Clinical molecular genetics evaluation in women with reproductive failures JO: Am J Reprod Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32710571 #FOAvip Molecular diagnostics is a rapidly growing branch of the clinical laboratory and has accelerated the advance of personalized medicine in the fields of pharmacogenomics, pharmacogenetics, and nutrigenomics. The versatility of molecular biology allows it to be effective in several medical fields that include reproduction, immunogenetics, and virology. Implementation of molecular and sequencing technology in reproductive medicine can add another layer of understanding to better define the causes behind infertility and recurrent reproductive loss. In the following, we examine current molecular methods for probing factors behind reproductive pregnancy loss including reverse transcription polymerase chain reaction and next generation sequencing (NGS). We review several current and potential genetic (DNA) and transcriptional (RNA)-based parameters in women with infertility that can be significant in diagnosis and treatment. These molecular factors can be inferred either from genomic DNA or RNA locally within the endometrium. Furthermore, we consider infection-based abnormalities such as human herpesvirus-6 and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Finally, we present future directions as well as data demonstrating the potential role of human endogenous retroviruses in pregnancy loss. We hope these discussions will assist the clinician in delineating some of the intricate molecular factors that can contribute to infertility and recurrent reproductive failures. Twit Text FOAVip Clinical molecular genetics evaluation in women with reproductive failures ????Am J Reprod Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32710571 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32710571 #FOAvip English Wikipedia <ref>{{Cite pmid|32710571}}</ref> Clinical molecular genetics evaluation in women with reproductive failures #MMPMID32710571 Bilal MY; Katara G; Dambaeva S; Kwak-Kim J; Gilman-Sachs A; Beaman KD Am J Reprod Immunol 2021[Apr]; 85 (4): e13313 PMID32710571show ga Molecular diagnostics is a rapidly growing branch of the clinical laboratory and has accelerated the advance of personalized medicine in the fields of pharmacogenomics, pharmacogenetics, and nutrigenomics. The versatility of molecular biology allows it to be effective in several medical fields that include reproduction, immunogenetics, and virology. Implementation of molecular and sequencing technology in reproductive medicine can add another layer of understanding to better define the causes behind infertility and recurrent reproductive loss. In the following, we examine current molecular methods for probing factors behind reproductive pregnancy loss including reverse transcription polymerase chain reaction and next generation sequencing (NGS). We review several current and potential genetic (DNA) and transcriptional (RNA)-based parameters in women with infertility that can be significant in diagnosis and treatment. These molecular factors can be inferred either from genomic DNA or RNA locally within the endometrium. Furthermore, we consider infection-based abnormalities such as human herpesvirus-6 and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Finally, we present future directions as well as data demonstrating the potential role of human endogenous retroviruses in pregnancy loss. We hope these discussions will assist the clinician in delineating some of the intricate molecular factors that can contribute to infertility and recurrent reproductive failures. |*Abortion, Spontaneous/genetics/metabolism/virology[MESH] |*COVID-19/genetics/metabolism[MESH] |*Gene Expression Regulation[MESH] |*Herpesvirus 6, Human/genetics/metabolism[MESH] |*Infertility, Female/genetics/metabolism[MESH] |*Roseolovirus Infections/metabolism[MESH] |*SARS-CoV-2/genetics/metabolism[MESH] |Endometrium/metabolism/virology[MESH] |Female[MESH]Clinical molecular genetics evaluation in women with reproductive fail(epmc).pdf DeepDyve Pubget Overpricing