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10.1016/j.healun.2020.06.016 http://scihub22266oqcxt.onion/10.1016/j.healun.2020.06.016 32709482!7318961!32709482     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Heart+Lung+Transplant 2020 ; 39 (10): 1081-1088 Nephropedia Template TP {{tp|p=32709482|t=2020. A case series of novel coronavirus infection in heart transplantation from 2 centers in the pandemic area in the North of Italy |pdf=|usr=}}{{32709482}} gab.com Text A case series of novel coronavirus infection in heart transplantation from 2 centers in the pandemic area in the North of Italy JO: J Heart Lung Transplant http://www.kidney.de/pget.php?&tw=1&pmid=32709482 #FOAvip BACKGROUND: Little is known about the coronavirus SARS-CoV-2 disease (COVID-19) in solid organ transplanted patients. We here report a series of heart transplanted patients with COVID-19 from two centers of Italy. METHODS: All heart transplanted patients of Transplant Centers of Bergamo and Torino with a microbiologically confirmed SARS-CoV-2 infection were enrolled. Data collection included clinical presentation, laboratory and radiological findings, treatment and outcome. Follow-up was performed by visit or phone. RESULTS: From February to March 2020 twenty-six heart transplanted patients (age 62+/-12 years; 77% males; time from transplant 10+/-10 years; 69% with comorbidities) had a microbiologically confirmed COVID-19. The most frequent symptom was fever, followed by cough. Seventeen patients had a pneumonia, 8 of them severe pneumonia. Seven patients died (27%) and 17 (65%) were hospitalized. Discontinuation of immunosuppression was associated with death (71 vs 21%, p=0.02). Conversely, all patients receiving steroids survived (p<0.001). Patients who received heart transplantation during COVID-19 outbreak survived and no acute graft rejection occurred. Patients who died were older than survivors, had a longer time from transplant and a worse clinical presentation at diagnosis. The current regimen enabled the prolonged survival and function of orthotopic cardiac xenografts in altogether 6 of 8 baboons, of which 4 were now added. These results exceed the threshold set by the Advisory Board of the International Society for Heart and Lung Transplantation. CONCLUSIONS: COVID-19 has a significant impact on long term heart transplanted patients. Conversely, SARS-CoV-2 infection seems to have a limited influence on more recent transplants. Our experience may suggest that heart transplantation programs can be maintained even during the pandemic phase if specific and tailored paths to prevent and to limit virus transmission are provided. Twit Text FOAVip A case series of novel coronavirus infection in heart transplantation from 2 centers in the pandemic area in the North of Italy ????J Heart Lung Transplant http://www.kidney.de/pget.php?&tw=1&pmid=32709482 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32709482 #FOAvip English Wikipedia <ref>{{Cite pmid|32709482}}</ref> A case series of novel coronavirus infection in heart transplantation from 2 centers in the pandemic area in the North of Italy #MMPMID32709482 Iacovoni A; Boffini M; Pidello S; Simonato E; Barbero C; Sebastiani R; Vittori C; Fontana A; Terzi A; De Ferrari GM; Rinaldi M J Heart Lung Transplant 2020[Oct]; 39 (10): 1081-1088 PMID32709482show ga BACKGROUND: Little is known about the coronavirus SARS-CoV-2 disease (COVID-19) in solid organ transplanted patients. We here report a series of heart transplanted patients with COVID-19 from two centers of Italy. METHODS: All heart transplanted patients of Transplant Centers of Bergamo and Torino with a microbiologically confirmed SARS-CoV-2 infection were enrolled. Data collection included clinical presentation, laboratory and radiological findings, treatment and outcome. Follow-up was performed by visit or phone. RESULTS: From February to March 2020 twenty-six heart transplanted patients (age 62+/-12 years; 77% males; time from transplant 10+/-10 years; 69% with comorbidities) had a microbiologically confirmed COVID-19. The most frequent symptom was fever, followed by cough. Seventeen patients had a pneumonia, 8 of them severe pneumonia. Seven patients died (27%) and 17 (65%) were hospitalized. Discontinuation of immunosuppression was associated with death (71 vs 21%, p=0.02). Conversely, all patients receiving steroids survived (p<0.001). Patients who received heart transplantation during COVID-19 outbreak survived and no acute graft rejection occurred. Patients who died were older than survivors, had a longer time from transplant and a worse clinical presentation at diagnosis. The current regimen enabled the prolonged survival and function of orthotopic cardiac xenografts in altogether 6 of 8 baboons, of which 4 were now added. These results exceed the threshold set by the Advisory Board of the International Society for Heart and Lung Transplantation. CONCLUSIONS: COVID-19 has a significant impact on long term heart transplanted patients. Conversely, SARS-CoV-2 infection seems to have a limited influence on more recent transplants. Our experience may suggest that heart transplantation programs can be maintained even during the pandemic phase if specific and tailored paths to prevent and to limit virus transmission are provided. |Aged[MESH] |COVID-19[MESH] |Cohort Studies[MESH] |Coronavirus Infections/*epidemiology/prevention & control[MESH] |Female[MESH] |Graft Rejection/prevention & control[MESH] |Graft Survival[MESH] |Heart Transplantation/methods/*statistics & numerical data[MESH] |Hospital Mortality/*trends[MESH] |Humans[MESH] |Immunosuppression Therapy[MESH] |Incidence[MESH] |Infection Control/methods[MESH] |Italy/epidemiology[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics/prevention & control/*statistics & numerical data[MESH] |Pneumonia, Viral/*epidemiology/prevention & control[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Assessment[MESH] |Severe Acute Respiratory Syndrome/diagnosis/*epidemiology[MESH]A case series of novel coronavirus infection in heart transplantation (epmc).pdf DeepDyve Pubget Overpricing