Lung Injury in COVID-19-An Emerging Hypothesis #MMPMID32709193
Alharthy A; Faqihi F; Memish ZA; Karakitsos D
ACS Chem Neurosci 2020[Aug]; 11 (15): 2156-2158 PMID32709193show ga
Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic phenomena ("dual hit" injury). Recently, severe neurological manifestations such as acute disseminated encephalomyelitis, which may be not linked to lung pathology, have been identified in COVID-19, contributing thus further to the versatility of its clinical features.