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10.1186/s12879-020-05281-3

http://scihub22266oqcxt.onion/10.1186/s12879-020-05281-3
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32703188!7376324!32703188
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suck abstract from ncbi


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pmid32703188      BMC+Infect+Dis 2020 ; 20 (1): 536
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  • Scent dog identification of samples from COVID-19 patients - a pilot study #MMPMID32703188
  • Jendrny P; Schulz C; Twele F; Meller S; von Kockritz-Blickwede M; Osterhaus ADME; Ebbers J; Pilchova V; Pink I; Welte T; Manns MP; Fathi A; Ernst C; Addo MM; Schalke E; Volk HA
  • BMC Infect Dis 2020[Jul]; 20 (1): 536 PMID32703188show ga
  • BACKGROUND: As the COVID-19 pandemic continues to spread, early, ideally real-time, identification of SARS-CoV-2 infected individuals is pivotal in interrupting infection chains. Volatile organic compounds produced during respiratory infections can cause specific scent imprints, which can be detected by trained dogs with a high rate of precision. METHODS: Eight detection dogs were trained for 1 week to detect saliva or tracheobronchial secretions of SARS-CoV-2 infected patients in a randomised, double-blinded and controlled study. RESULTS: The dogs were able to discriminate between samples of infected (positive) and non-infected (negative) individuals with average diagnostic sensitivity of 82.63% (95% confidence interval [CI]: 82.02-83.24%) and specificity of 96.35% (95% CI: 96.31-96.39%). During the presentation of 1012 randomised samples, the dogs achieved an overall average detection rate of 94% (+/-3.4%) with 157 correct indications of positive, 792 correct rejections of negative, 33 incorrect indications of negative or incorrect rejections of 30 positive sample presentations. CONCLUSIONS: These preliminary findings indicate that trained detection dogs can identify respiratory secretion samples from hospitalised and clinically diseased SARS-CoV-2 infected individuals by discriminating between samples from SARS-CoV-2 infected patients and negative controls. This data may form the basis for the reliable screening method of SARS-CoV-2 infected people.
  • |Animals[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |Bronchi/chemistry/virology[MESH]
  • |COVID-19[MESH]
  • |Case-Control Studies[MESH]
  • |Coronavirus Infections/*diagnosis/*virology[MESH]
  • |Dogs[MESH]
  • |Double-Blind Method[MESH]
  • |Humans[MESH]
  • |Mass Screening/*methods[MESH]
  • |Odorants/*analysis[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Pilot Projects[MESH]
  • |Pneumonia, Viral/*diagnosis/*virology[MESH]
  • |SARS-CoV-2[MESH]
  • |Saliva/chemistry/virology[MESH]


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