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10.1177/1076029620943671

http://scihub22266oqcxt.onion/10.1177/1076029620943671
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32702995!7383642!32702995
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suck abstract from ncbi


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pmid32702995      Clin+Appl+Thromb+Hemost 2020 ; 26 (ä): 1076029620943671
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  • Coagulation Status and Venous Thromboembolism Risk in African Americans: A Potential Risk Factor in COVID-19 #MMPMID32702995
  • Frydman GH; Boyer EW; Nazarian RM; Van Cott EM; Piazza G
  • Clin Appl Thromb Hemost 2020[Jan]; 26 (ä): 1076029620943671 PMID32702995show ga
  • Severe acute respiratory syndrome coronavirus 2 infection (COVID-19) is known to induce severe inflammation and activation of the coagulation system, resulting in a prothrombotic state. Although inflammatory conditions and organ-specific diseases have been shown to be strong determinants of morbidity and mortality in patients with COVID-19, it is unclear whether preexisting differences in coagulation impact the severity of COVID-19. African Americans have higher rates of COVID-19 infection and disease-related morbidity and mortality. Moreover, African Americans are known to be at a higher risk for thrombotic events due to both biological and socioeconomic factors. In this review, we explore whether differences in baseline coagulation status and medical management of coagulation play an important role in COVID-19 disease severity and contribute to racial disparity trends within COVID-19.
  • |*Betacoronavirus[MESH]
  • |*Black or African American/genetics[MESH]
  • |*Pandemics[MESH]
  • |Anemia, Sickle Cell/blood/ethnology[MESH]
  • |Anticoagulants/therapeutic use[MESH]
  • |Blood Proteins/analysis/genetics[MESH]
  • |COVID-19[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/blood/complications/*ethnology[MESH]
  • |Factor VIII/analysis[MESH]
  • |Female[MESH]
  • |Fibrin Fibrinogen Degradation Products/analysis[MESH]
  • |Genetic Association Studies[MESH]
  • |Genetic Predisposition to Disease[MESH]
  • |Healthcare Disparities[MESH]
  • |Humans[MESH]
  • |Lupus Erythematosus, Systemic/blood/ethnology[MESH]
  • |Male[MESH]
  • |Patient Selection[MESH]
  • |Pneumonia, Viral/blood/complications/*ethnology[MESH]
  • |Polymorphism, Single Nucleotide[MESH]
  • |Prevalence[MESH]
  • |Renal Insufficiency, Chronic/blood/ethnology[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Social Determinants of Health[MESH]
  • |Socioeconomic Factors[MESH]
  • |Thrombophilia/blood/drug therapy/*ethnology/etiology[MESH]


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